Evidence map›Paper›PMID 41969518›Full record

ArticleTranslational cancer research2026

MicroRNA-663a upregulation upon ARID1A depletion promotes the growth and migration of esophageal cancer cells by targeting FKBP8.

Hongli Liao, Chunyi Ren, Yi Jiang, Fengxiang Wang, Yanyan Dai

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Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hongli LiaoDepartment of Pathology, Wenzhou Central Hospital, Affiliated to Wenzhou Medical University, Wenzhou, China.
Chunyi RenDepartment of Pathology, Wenzhou Central Hospital, Affiliated to Wenzhou Medical University, Wenzhou, China.
Yi JiangDepartment of Pathology, Wenzhou Central Hospital, Affiliated to Wenzhou Medical University, Wenzhou, China.
Fengxiang WangDepartment of Pathology, Wenzhou Central Hospital, Affiliated to Wenzhou Medical University, Wenzhou, China.
Yanyan DaiDepartment of Pathology, Wenzhou Central Hospital, Affiliated to Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: ARID1A loss has been shown to promote the development and progression of cancers by modulating different target genes, including microRNAs (miRs). This study was performed to identify ARID1A-regulated miRs involved in esophageal cancer progression. Methods: ARID1A expression in esophageal cancer cell lines was knocked down and the expression of candidate miRs that were differentially expressed between esophageal cancer and adjacent normal tissues was examined. The role of ARID1A-regulated miRs in the growth and migration of esophageal cancer cells was determined. Results: Conclusions: The miR-663a/FKBP8 axis regulated by ARID1A plays a critical role in esophageal cancer cell proliferation and migration and represents a potential therapeutic target for this malignancy.

Indexed as

ARID1Aesophageal cancermiR-663aoncogenesis

Identifiers

PMID41969518
PMCPMC13067029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.