ReviewFrontiers in oral health2026
Association between periodontal disease and chronic obstructive pulmonary disease: an umbrella review.
Review in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Oral health in chronic obstructive pulmonary disease: are physicians prepared to integrate it into routine care?Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: To evaluate the strength and methodological quality of evidence regarding the association between periodontal disease (PD) and chronic obstructive pulmonary disease (COPD) through an umbrella review. Materials and methods: A comprehensive search was conducted through April 2025 in PubMed, Cochrane Library, Scopus, Embase, Web of Science, Google Scholar, ProQuest Dissertations and Theses, and OpenGrey. Systematic reviews (SRs), with or without meta-analysis, investigating the association between PD and COPD were included without time or language restrictions. Narrative reviews, primary studies, protocols, and non-systematic reports were excluded. Methodological quality was assessed using AMSTAR-2. The degree of primary study overlap was calculated using the Corrected Covered Area (CCA) index. Due to high overlap (CCA = 14.45%) and clinical heterogeneity, no Results: Of 313 identified records, 12 SRs comprising 145 primary studies were included. Six reviews were rated as high confidence, one as low confidence, and five as critically low confidence according to AMSTAR-2. Most SRs reported a positive association between PD and COPD. However, the magnitude and statistical significance of the association varied according to periodontal parameters, COPD outcomes, and smoking status. Conclusion: Current evidence suggests a likely association between PD and COPD, although the relationship may be influenced by shared risk factors such as smoking and methodological heterogeneity. Integrating periodontal assessment into COPD management may be clinically relevant, but high-quality prospective studies are needed to clarify causal pathways. Systematic Review Registration: Open Science Framework (OSF), https://doi.org/10.17605/OSF.IO/YTXB6.
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Registered trials
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