Evidence map›Paper›PMID 41969101›Full record

ReviewBioMed research international2026

Effects of CMV on T and NK Cells; With Emphasis on Immunometabolism.

Haideh Namdari, Mohsen Keshavarz, Maryam Hosseini, Farzad Parvizpour, Asrin Emami, Elahe Izadi, Milad Shahbazi Asl, Mehdi Shahgolzari, Farhad Rezaei

Abstract readReview
In one paragraph

Review in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haideh NamdariIranian Tissue Bank and Research Center, Gene, Cell and Tissue Research Institute, Tehran University of Medical sciences, Tehran, Iran, tums.ac.ir.
Mohsen KeshavarzThe Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran, bpums.ac.ir.
Maryam HosseiniTrauma Research Center, Shahid Rajaee (Emtiaz) Trauma Hospital, Shiraz University of Medical Sciences, Shiraz, Iran, sums.ac.ir.
Farzad ParvizpourDepartment of Molecular Medicine, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran, muk.ac.ir.
Asrin EmamiIranian Tissue Bank and Research Center, Gene, Cell and Tissue Research Institute, Tehran University of Medical sciences, Tehran, Iran, tums.ac.ir.
Elahe IzadiIranian Tissue Bank and Research Center, Gene, Cell and Tissue Research Institute, Tehran University of Medical sciences, Tehran, Iran, tums.ac.ir.
Milad Shahbazi AslDepartment of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran, ut.ac.ir.
Mehdi ShahgolzariDepartment of Medical Nanotechnology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, zums.ac.ir.
Farhad RezaeiVirology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0002-5957-6691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CMV is masterful at manipulating stress responses and conducting them in a way that yields beneficial outcomes. CMV always causes metabolic changes in the infected cells. However, nutritional status affects the pattern of events following CMV infection. Oxidative phosphorylation (OXPHOS) and glycolysis are two vital pathways for energy generation in mammalian cells, which differ in terms of ATP production and location. Understanding metabolic alterations required for CMV infection may lead to the design of novel therapeutic methods based on targeted inhibition of these cellular metabolic pathways. This review explores how CMV mimics, exploits, or interferes with the host cell, with emphasis on immunometabolism, and how, in doing so, it may evade immune responses.

Indexed as

CytomegalovirusCytomegalovirus InfectionsKiller Cells, NaturalT-LymphocytesAdenosine TriphosphateAnimalsGlycolysisHumansOxidative PhosphorylationAdenosine TriphosphateATPCMVglycolysisimmunometabolismphosphorylation

Identifiers

PMID41969101
PMCPMC13071538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.