Evidence map›Paper›PMID 41969021›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Characterizing ferrous versus ferric iron in Alzheimer's disease using X-ray fluorescence imaging and XANES spectroscopy.

Dean Tran, Marios Georgiadis, Philip DiGiacomo, Jeff Nirschl, Inma Cobos, Jarrett Rosenberg, Nicholas Edwards, Sharon Bone, Samuel Webb, Michael Zeineh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dean TranDepartment of Radiology, Stanford University, Stanford, CA, USA.ORCID 0009-0006-5575-6464
Marios GeorgiadisDepartment of Radiology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-0733-4559
Philip DiGiacomoDepartment of Radiology, Stanford University, Stanford, CA, USA.
Jeff NirschlDepartment of Pathology, Stanford University, Stanford, CA, USA.
Inma CobosDepartment of Pathology, Stanford University, Stanford, CA, USA.
Jarrett RosenbergDepartment of Radiology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-2706-3290
Nicholas EdwardsStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.
Sharon BoneStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.
Samuel WebbStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.
Michael ZeinehDepartment of Radiology, Stanford University, Stanford, CA, USA.

Funding

Iron as an Imaging Biomarker for Inflammation in ADR01AG061120 · NIA · STANFORD UNIVERSITY · PI ZEINEH, MICHAEL M · 2019 to 2023
$3.5M
NOVEL EXOSOME BIOMARKERS OF IRON PATHOLOGY IN ADR21AG072675 · NIA · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN, ZEINEH, MICHAEL M · 2021 to 2021
$433k
Quantifying myelin degeneration in ADR03AG083702 · NIA · STANFORD UNIVERSITY · PI GEORGIADIS, MARIOS · 2024 to 2024
$305k
NIA NIH HHS R01 AG061120NIA NIH HHS R03 AG083702NIA NIH HHS R21 AG072675
6 · The paper itself

Abstract

BackgroundThe accumulation of iron, such as ferrous Fe

Indexed as

Alzheimer DiseaseFerrous CompoundsHippocampusIronX-Ray Absorption SpectroscopyAgedAged, 80 and overFemaleHumansMaleSpectrometry, X-Ray EmissionFerrous CompoundsIronAlzheimer's diseasehippocampusironoxidative stresssynchrotronx-ray absorption spectroscopy

Identifiers

PMID41969021
PMCPMC13335707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.