Evidence map›Paper›PMID 41968525›Full record

ReviewThe Plant journal : for cell and molecular biology2026

Plant NLRs are getting into higher-order architectures.

Nayun Kim, Eunyoung Chae, Ji-Joon Song

Abstract readReview
In one paragraph

Review in The Plant journal : for cell and molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nayun KimDepartment of Biological Sciences, KI for BioInnovation, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Korea.
Eunyoung ChaeDepartment of Biology, University of Oxford, South Parks Road, Oxford, OX1 3EL, UK.
Ji-Joon SongDepartment of Biological Sciences, KI for BioInnovation, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Korea.

Funding

Ministry of Science and ICT, South Korea GISTInnoCOREKH0860National Research Foundation of Korea RS-2024-00333346National Research Foundation Singapore NRF-CRP22-2019-0001
6 · The paper itself

Abstract

Nucleotide-binding leucine-rich repeat (NLR) proteins are central components of the plant immune system that detect pathogen-derived effectors or modifications of host proteins within the cell to activate immune responses. NLRs have co-evolved with pathogens in an ongoing evolutionary arms race, leading to diversification of NLR structures and the establishment of highly interconnected immune networks. Recent studies have shown that NLRs dynamically assemble into higher-order structures, including multimeric complexes, filaments, and biomolecular condensates. These higher-order architectures are essential for NLR activation, intracellular signaling, and interactions with host proteins. Structural and biochemical analyses have revealed both conserved and divergent mechanisms underlying these assemblies. In this review, we summarize recent advances in understanding the formation and functional significance of higher-order NLR assemblies.

Indexed as

NLR ProteinsPlant ImmunityPlant ProteinsPlantsInnate Immunity RecognitionSignal TransductionNLR ProteinsPlant Proteinsbiomolecular condensateseffector‐triggered immunityfilamenthigh‐order structuresnucleotide‐binding leucine‐rich repeatresistosome

Identifiers

PMID41968525
PMCPMC13071261

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.