Evidence map›Paper›PMID 41968380›Full record

ReviewCancer reports (Hoboken, N.J.)2026

Bacterial Infections Role in Gynecological Cancers Development: Narrative Review.

Robab Azargun, Maryam Azargoon, Zahra Asefy, Mina Yekani, Vahideh Tarhriz, Fatemeh Yeganeh, Mohammad Yousef Memar, Shirin Eyvazi

Abstract readReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robab AzargunMedicinal Plants Research Center, Maragheh University of Medical Sciences, Maragheh, Iran.ORCID 0000-0001-8722-6093
Maryam AzargoonDepartment of Knowledge and Information Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.ORCID 0000-0001-6581-7079
Zahra AsefyMedicinal Plants Research Center, Maragheh University of Medical Sciences, Maragheh, Iran.ORCID 0000-0002-3176-4105
Mina YekaniPediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0002-8991-3521
Vahideh TarhrizCardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.ORCID 0000-0002-3018-9313
Fatemeh YeganehMicrobiology Department, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0003-2151-3385
Mohammad Yousef MemarInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0002-0328-4753
Shirin EyvaziDepartment of Immunology, Mayo Clinic, Phoenix, Arizona, USA.ORCID 0000-0002-9216-6512

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGynecological cancers are among the most common cancers in women that affect female reproductive organs. The most common gynecological cancers are ovarian, cervical, uterine/endometrial, vaginal, and vulvar cancer. Women's reproductive organs have a dynamic and relative microbial balance. The disruption in the balance of the microbiome could result in numerous gynecological diseases, as well as, gynecological cancers. In this study, we aimed to review new findings on the role of different bacterial infections in various types of gynecological cancers. RECENT

findingsThe role of bacterial infection, as an external factor, has been established in several cancers. However, the ways in which bacteria can promote the development of cancer are not fully understood. It seems that inflammation induced by bacterial infections could promote carcinogenesis. In addition, bacterial toxins and effector proteins play important roles in the progression of cancer. In this review, we attempt to present the different bacterial infections, which have been linked to gynecological cancers development. According to different researches, Chlamydia, Mycoplasma, and Bacteroides spp. are the most common bacterial infections associated with gynecological cancers.

conclusionEvaluation of microbiome in reproductive organs of the patients with gynecological cancer and studies on prevention and control of the infections in the patients could be useful in verification of pathogenesis of the diseases and also founding suitable therapeutic interventions.

Indexed as

Bacterial InfectionsGenital Neoplasms, FemaleFemaleHumansMicrobiotabacterial infectionChlamydiagynecological cancersmicrobiotaMycoplasmareproductive organs

Identifiers

PMID41968380
PMCPMC13070870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.