Evidence map›Paper›PMID 41968327›Full record

ArticleJournal of cardiothoracic surgery2026

Concomitant left atrial appendage exclusion during cardiac surgery: a single-center case series on technique profile, residual flow, and early safety.

Masafumi Kudo, Hideki Tsubota, Yuki Akaguma, Masanori Honda, Hitoshi Okabayashi

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Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Masafumi KudoDepartment of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Katsuragosho-cho, Nishikyo-ku, Kyoto, 615-8087, Japan. varone01@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0009-0008-7642-6020
Hideki TsubotaDepartment of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Katsuragosho-cho, Nishikyo-ku, Kyoto, 615-8087, Japan.
Yuki AkagumaDepartment of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Katsuragosho-cho, Nishikyo-ku, Kyoto, 615-8087, Japan.
Masanori HondaDepartment of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Katsuragosho-cho, Nishikyo-ku, Kyoto, 615-8087, Japan.
Hitoshi OkabayashiDepartment of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Katsuragosho-cho, Nishikyo-ku, Kyoto, 615-8087, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConcomitant left atrial appendage exclusion is increasingly performed during cardiac surgery in patients with atrial fibrillation. However, real-world data on procedural variations, closure integrity, and early safety are limited.

methodsWe retrospectively reviewed 86 patients with atrial fibrillation who underwent concomitant left atrial appendage exclusion during cardiac surgery at a single center between 2012 and 2025. Nineteen patients underwent left atrial appendage occlusion using suture-based techniques or a closure device, and 67 underwent left atrial appendage resection with closure using sutures or a stapler. Residual flow was assessed using intraoperative transesophageal echocardiography, and outcomes were evaluated during follow-up.

resultsPatients in the occlusion group more often had longer atrial fibrillation duration, vitamin K antagonist use, and previous cardiac surgery. Mitral valve procedures were more frequently combined with occlusion, whereas maze ablation was more common in the resection group. Intraoperative residual flow was detected in three patients (16%) after occlusion and in none after resection. Both approaches showed favorable early safety, with no 30-day mortality and low reoperation rates due to bleeding. Differences in sinus rhythm and anticoagulation at three months were observed, but were likely influenced by concomitant maze procedures. Differences in long-term survival were also observed but should be interpreted cautiously because of baseline imbalances and unequal follow-up duration.

conclusionsIn this single-center retrospective case series, suture-based occlusion was associated with residual flow in a subset of patients, whereas no residual flow was detected after resection using intraoperative echocardiography. Both approaches showed acceptable early safety. Larger multicenter studies with standardized follow-up imaging are needed to clarify closure durability and the long-term clinical outcomes.

Indexed as

Atrial AppendageAtrial FibrillationCardiac Surgical ProceduresLeft Atrial Appendage ClosureAgedEchocardiography, TransesophagealFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesAtrial fibrillationCardiac surgeryLeft atrial appendageOcclusionResectionResidual flowSuture techniques

Identifiers

PMID41968327
PMCPMC13214353

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.