ArticleMethods in molecular biology (Clifton, N.J.)2026
Galleria mellonella to Study Aspergillus Infections and Antifungal Efficacy by Traditional Readouts and Novel BL-Imaging Techniques.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Galleria mellonella (greater wax moth) larvae have emerged as a valuable alternative in vivo model for studying fungal infections, including aspergillosis, due to their advantages such as ease of use, low cost, and ability to survive at mammalian body temperatures. Galleria larvae are useful for evaluating fungal virulence, host-pathogen interactions, and antifungal toxicity and efficacy. Recent studies have incorporated bioluminescence (BL) imaging, which enhances the utility of the model by enabling noninvasive, real-time monitoring of fungal burden and disease progression in individual animals. Together, these advantages make G. mellonella an effective and ethically favorable platform for preclinical aspergillosis research, perfectly aligning with 3R principles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.