Evidence map›Paper›PMID 41968219›Full record

Observational studyJournal of robotic surgery2026

Robotic Liver Resection for Gallbladder Cancer: Does Common Bile Duct Resection Matter? An International Propensity-Matched Study.

Giuseppe Esposito, Anna Axentiev, Sharona Ross, Hasan Al Harakeh, Roberta Odorizzi, John Martinie, Riccardo Memeo, Andrea Belli, Pier Cristoforo Giulianotti, Roberto I Troisi and 12 more

Erratum issuedAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Giuseppe EspositoHepatopancreatobiliary Surgery, Digestive Health Institute, AdventHealth Tampa, Tampa, Florida, USA.
Anna AxentievHepatopancreatobiliary Surgery, Digestive Health Institute, AdventHealth Tampa, Tampa, Florida, USA.
Sharona RossHepatopancreatobiliary Surgery, Digestive Health Institute, AdventHealth Tampa, Tampa, Florida, USA.
Hasan Al HarakehHepatopancreatobiliary Surgery, Digestive Health Institute, AdventHealth Tampa, Tampa, Florida, USA.
Roberta OdorizziHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.
John MartinieDivision Of HPB Surgery, Carolinas Medical Center, Atrium Health, Charlotte, NC, USA.
Riccardo MemeoUnit Of Hepatobiliary And Pancreatic Surgery, Miulli Hospital, Acquaviva Delle Fonti, Bari, Italy.
Andrea BelliDepartment Of Surgical Oncology, Hepatobiliary And Pancreatic Unit - Istituto, IRCCS Fondazione ''G PASCALE'', Tumori Di Napoli, Naples, Italy.
Pier Cristoforo GiulianottiDivision Of Minimally Invasive, General & Robotic Surgery (CHIEF), University Of Illinois At Chicago, Chicago, USA.
Roberto I TroisiHPB And Transplant Surgery Unit, Department Of Clinical Medicine And Surgery, Federico II University Hospital, Naples, Italy.
Brian K P GohDepartment Of Hepatopancreatobiliary And Transplant Surgery, Singapore General Hospital And National Cancer Centre Singapore, Singapore, Singapore.
Mira Khaldoun EidHepatopancreatobiliary Surgery, Digestive Health Institute, AdventHealth Tampa, Tampa, Florida, USA.
Raffaele RomitoGeneral Surgery II Unit, A.O.U Maggiore Della Carità Di Novara, Novara, Italy.
Garnet VanterpoolHepatopancreatobiliary Surgery, Digestive Health Institute, AdventHealth Tampa, Tampa, Florida, USA.
Alfredo GuglielmiDepartment Of Surgery, Dentistry, Gynecology And Pediatrics, University Of Verona, GB Rossi Hospital, Verona, Italy.
Adrian Kah Heng ChiowHepatobiliary Service, Department Of Surgery, Changi General Hospital, Simei, Singapore.
Luca MorelliGeneral Surgery Unit, Department Of Translational Research And New Technologies In Medicine And Surgery, University Of Pisa, Pisa, Italy.
Victor Lopez-LopezClinic And University Virgen De La Arrixaca Hospital, Murcia, Spain.
Fabrizio Di BenedettoHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.
Luca MoraldiDepartment Of Hepato-Bilio-Pancreatic Surgery, AOU Careggi Firenze, Florence, Italy.
Benedetto IelpoGeneral Surgery Unit, Department Of Translational Research And New Technologies In Medicine And Surgery, Hospital Del Mar, Barcelona, Spain.
Iswanto SucandyHepatopancreatobiliary Surgery, Digestive Health Institute, AdventHealth Tampa, Tampa, Florida, USA. Iswanto.Sucandy@adventhealth.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMinimally invasive common bile duct resection (CBDR) for gallbladder cancer (GBC) is technically demanding, and comparative perioperative and oncological outcomes of robotic liver resection (LR) with versus without CBDR remain poorly characterized. We conducted a propensity score-matched (PSM) study evaluating outcomes of robotic GBC resection with or without CBDR.

methodsThis international, multicenter retrospective study included patients undergoing fully-robotic LR for non-metastatic GBC, with or without CBDR. Outcomes were analyzed before and after 1:1 PSM across 18 high-volume hepatobiliary centers between 2013 and 2024.

resultsA total of 138 patients were included, 21 (15.2%) undergoing CBDR and 117 (84.8%) did not. Before matching, perioperative outcomes were comparable between CBDR and non-CBDR. After matching, no significant differences were observed in operative time, blood loss (175 vs. 100 mL, p = 0.292), conversion to open, bile leak (12.5% vs. 12.5%, p = 0.536), Clavien–Dindo ≥ III complications (12.5% vs. 12.5%, p = 1), or length of hospitalization (5 vs. 4 days; p = 0.084). No differences were found in lymph node yield (8.5 vs. 7; p = 0.437), recurrence, or 90-day mortality (12.5% vs. 18.8%, p = 1). After median follow-up of 17 months, overall and disease-free survivals were comparable both before and after PSM. CBDR was not an independent predictor of disease recurrence [HR 2.36, (95% CI 0.72–7.72); p = 0.155] or overall mortality and showed no association with retrieval of ≥ 6 lymph nodes [OR 1.00, (95% CI 0.37–2.68); p = 1] or R0 margins.

conclusionRobotic CBDR for GBC is safe and feasible, achieving perioperative clinical and oncological outcomes comparable to robotic LR without CBDR.

Indexed as

Common Bile DuctGallbladder NeoplasmsHepatectomyRobotic Surgical ProceduresAgedFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsPropensity ScoreRetrospective StudiesTreatment OutcomeCommon bile duct resectionGallbladder cancerOncological outcomesRadical lymphadenectomyRobotic surgery

Identifiers

PMID41968219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.