Evidence map›Paper›PMID 41968098›Full record

ArticleJournal of animal science2026

The supplementation of lubabegron or ractopamine hydrochloride in the summer improved growth performance but did not impact rumination, mobility scores, and behaviors in feedlot cattle in the United States†.

Huey Yi Loh, Paxton A Sullivan, Jeniffer Backes-Kincher, Michelle Calvo-Lorenzo, Terry E Engle, Lily Edwards-Callaway

Abstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huey Yi LohDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, United States.ORCID 0009-0009-5603-8343
Paxton A SullivanDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, United States.ORCID 0000-0001-7715-2828
Jeniffer Backes-KincherDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, United States.
Michelle Calvo-LorenzoElanco Animal Health, Indianapolis, IN 46221, United States.
Terry E EngleDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, United States.
Lily Edwards-CallawayDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, United States.ORCID 0000-0002-0737-9899

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of β-ligand supplementation on growth performance, carcass characteristics, rumen parameters, mobility, and behavior in feedlot steers finished in the summer months. Three hundred sixty Angus crossbred steers were ranked by body weight (BW) and randomly assigned to one of three treatments: 1) Control (no β-ligand), 2) Ractopamine Hydrochloride (RAC; 300 mg·animal-1·d-1), or 3) Lubabegron (LUB; 36 mg·animal-1·d-1). RAC and LUB were fed for the final 35 d of the finishing period, followed by a 4 d voluntary withdrawal period prior to slaughter. Steers were housed in feedlot pens (10 head/pen; 12 pens/treatment). A steam flaked corn-based diet with the appropriate treatment was delivered once daily to provide cattle ad libitum access to feed over a 24 h period. Body weights and mobility scores were obtained at the beginning of the experiment and every 14 d throughout the supplementation period. Weekly in-pen behavior was observed via 24 h video footage, using instantaneous sampling with a 10-minute scan interval. Rumen boluses were administered to 2 steers per pen before the initiation of the experiment to continuously monitor reticulorumen temperature, pH, and rumination events. Ambient environmental conditions were recorded throughout the study. Post-slaughter carcass characteristics were evaluated. The RAC and LUB supplemented steers had greater (P < 0.05) final BW, average daily gains, and feed efficiencies compared to controls. Steers supplemented with RAC and LUB had greater (P < 0.05) hot carcass weights and longissimus muscle areas than control steers. No treatment differences (P > 0.05) were detected for dressing percentage, quality grade, subcutaneous fat depth, USDA yield grade, and meat color. There was no treatment effect (P > 0.10) for reticulorumen pH, temperature, or rumination time. Similar (P > 0.05) mobility score distributions were observed across treatments. The majority of cattle exhibited normal mobility over the course of the study. Three-way interactions (P < 0.01) between treatment, week, and time of day were observed for drinking, standing, and lying behaviors. A two-way interaction (P < 0.05) between treatment and week was detected for locomotion behavior. In summary, RAC and LUB supplementation to feedlot steers during the summer months improved growth performance and carcass characteristics and had no impact on mobility scores, rumen parameters, or behaviors when compared to control steers.

Indexed as

Adrenergic beta-AgonistsPhenethylaminesRumination, DigestiveAnimal FeedAnimalsBehavior, AnimalBody CompositionCattleDietDietary SupplementsMaleRandom AllocationSeasonsTrimethylsilyl CompoundsUnited StatesAdrenergic beta-AgonistsPhenethylaminesractopamineTrimethylsilyl CompoundsZilpaterolbehaviorheat stresswelfareβ-agonistβ-ligands

Identifiers

PMID41968098
PMCPMC13094938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.