SynthesisThe Journal of international medical research2026
Point-of-care ultrasound for central venous catheter confirmation and complications in the emergency department: A systematic review and meta-analysis.
Synthesis in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
BackgroundCentral venous catheter malposition and pneumothorax remain clinically important complications after insertion. Many emergency departments still rely on post-procedural chest radiography, which may delay catheter use. We evaluated the diagnostic accuracy and workflow impact of point-of-care ultrasound for confirming central venous catheter position and detecting complications in the emergency department.MethodsWe conducted a systematic review and diagnostic test accuracy meta-analysis (International Prospective Register of Systematic Reviews (PROSPERO): CRD420251065638) following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy Studies (PRISMA-DTA) and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. The PubMed, Embase, Cochrane Library, Web of Science Core Collection, and Scopus databases were searched from inception to 1 December 2025. Studies were considered eligible for inclusion if they enrolled adults undergoing internal jugular or subclavian central venous catheter insertion in emergency department settings and compared bedside point-of-care ultrasound (cardiac/contrast-enhanced "swirl/bubble" techniques and/or lung ultrasound) with chest radiography and/or computed tomography. For catheter malposition, pooled sensitivity and specificity were estimated using a bivariate random-effects model; pneumothorax accuracy and time outcomes were summarized descriptively due to sparse events.ResultsA total of eight prospective studies (801 central venous catheter insertions) were included. Seven studies contributed estimable 2 × 2 data for malposition. Point-of-care ultrasound showed pooled sensitivity of 0.81 (95% confidence interval: 0.50-0.95) and specificity of 0.99 (95% confidence interval: 0.96-1.00), with hierarchical summary receiver operating characteristic-area under the curve of 0.99 (95% confidence interval: 0.97-0.99), positive likelihood ratio of 137.83 (95% confidence interval: 22.04-862.02), negative likelihood ratio of 0.19 (95% confidence interval: 0.06-0.62), and diagnostic odds ratio of 737.34. Heterogeneity was substantial (I
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