ReviewTrends in cell biology2026
Generating exosome subtypes: diverse membrane origins and mergers.
Review in Trends in cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- EV-Mediated Oncogenic Regulation in Lung Cancer and Clinical Translation: From Liquid Biopsy to Targeted Delivery Systems.International journal of nanomedicine · 2026Review
- Extracellular vesicles inEXO : beyond the cell · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exosomes are formally defined as extracellular vesicles, which are formed in compartments with endosomal origin by the inward budding of the endosomal limiting membrane. Recent analyses of the dynamic events within exosome-generating compartments have overturned the dogma that only late endosomal membranes produce exosomes. It is now clear that recycling endosomal, autophagic, regulated secretory, and other organelle membranes contribute to exosome production. In this opinion article, we discuss studies demonstrating the critical roles of membrane origins and mergers, together with intracompartmental microenvironments, in generating intraluminal vesicle and exosome subtypes with diverse physiological and pathological functions, both inside and outside the secreting cell. These findings provide significant opportunities to develop novel strategies that overcome the current challenges of detecting and targeting disease-relevant exosomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.