ArticleContact dermatitis2026
Allergen Content of Inactive Ingredients in Best-Selling Sunscreens: A Comparison of Key Product Features.
Article in Contact dermatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIrritant and allergic contact dermatitis (ACD) caused by sunscreens may affect patient adherence and photoprotection.
objectivesWe aimed to compare the presence of inactive allergens from the North American 80 Comprehensive Series (NAC-80) across top-selling sunscreens.
methodsWe conducted a cross-sectional analysis of inactive ingredient lists from all reported best-selling sunscreens from the three largest American online retailers: Amazon.com, Target.com and Walmart.com. Using a custom text-matching algorithm and manual review, we identified NAC-80 allergens and quantified allergen counts per product. We compared inactive allergen load in tinted versus non-tinted, organic versus inorganic ultraviolet (UV) filters, vehicle and various marketed features in sunscreens.
resultsWe reviewed 176 products. Vitamin E was the most common allergen, followed by acrylate-containing copolymers/crosspolymers, fragrance, and parabens. Organic, spray and sport sunscreens had significantly more allergens than inorganic, stick and non-sport sunscreens, respectively. Tinted and face sunscreens had significantly fewer allergens than non-tinted and body sunscreens.
conclusionsAllergen content in inactive ingredients varies among best-selling sunscreens, potentially affecting their safety and tolerability. Dermatologists should consider the allergenic potential of not only active but also inactive ingredients of sunscreens when counselling patients.
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