ArticleThe Korean journal of pain2026
Hypoalgesic effects, safety, and feasibility of a 6-minute high-lung-volume static apnea intervention.
Article in The Korean journal of pain, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Repeated apneas may induce hypoalgesia, but the impact of high-lung-volume static apneas remains unexplored. Methods: Eighty-one healthy participants were randomized into an apnea group (AG) or control group (CG). The AG performed a 6-minute static intermittent apnea at high lung volume, while the CG breathed normally in supine. Pressure pain thresholds (PPTs) at the thumb, tibialis anterior and the 7 Results: ANCOVA showed no significant differences in PPT between groups in the thumb (mean difference [MD] = 0.306 kg/cm Conclusions: High-lung-volume static apneas showed no clear hypoalgesic effect and participants reported slightly greater discomfort. Further studies should explore the dose-effect relationships in healthy and clinical populations.
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