Evidence map›Paper›PMID 41967786›Full record

ArticleNeuroImage2026

A hierarchical brain MRI atlas of the coppery titi monkey (Plecturocebus cupreus).

Alita Jesal D Almeida, Brad A Hobson, Anelise Caceres, Sarah Tam, John P Paulus, Claudia Manca, Anand A Joshi, Sara M Freeman, Karen L Bales, Abhijit J Chaudhari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alita Jesal D AlmeidaDepartment of Biomedical Engineering, University of California-Davis College of Engineering, Davis, CA, 95616, USA; Department of Radiology, University of California-Davis School of Medicine, Sacramento, CA, 95817, USA.
Brad A HobsonCenter for Molecular and Genomic Imaging, University of California-Davis, Davis, CA, 95616, USA.
Anelise CaceresDepartment of Biomedical Engineering, University of California-Davis College of Engineering, Davis, CA, 95616, USA.
Sarah TamCenter for Molecular and Genomic Imaging, University of California-Davis, Davis, CA, 95616, USA.
John P PaulusDepartment of Neuroscience, University of California-Davis Center for Neuroscience, Davis, CA 95616, USA.
Claudia MancaDepartment of Psychology, University of California-Davis College of Letters and Science, Davis, CA 95616, USA.
Anand A JoshiMing Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA 90089-2560, USA.
Sara M FreemanDepartment of Biology, Utah State University, Logan, UT 84322, USA.
Karen L BalesDepartment of Psychology, University of California-Davis College of Letters and Science, Davis, CA 95616, USA; California National Primate Research Center, Davis, CA 95616, USA. Electronic address: klbales@ucdavis.edu.
Abhijit J ChaudhariDepartment of Radiology, University of California-Davis School of Medicine, Sacramento, CA, 95817, USA; Center for Molecular and Genomic Imaging, University of California-Davis, Davis, CA, 95616, USA; California National Primate Research Center, Davis, CA 95616, USA. Electronic address: ajchaudhari@ucdavis.edu.

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate IntoxicationU54NS127758 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Pamela J Lein · 2022 to 2026
$17.2M
Kappa opioid and oxytocin interactions in social buffering and separationR01MH125411 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BALES, KAREN L. · 2021 to 2025
$3.6M
Multimodality PET/CT Scanner for Small Animal ImagingS10OD030440 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J · 2022 to 2022
$878k
Imaging biomarkers of early synaptic changes in a preclinical model of Alzheimer’s diseaseR21AG064599 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J, LEIN, PAMELA J · 2019 to 2020
$432k
Quantifying synaptic density loss in a monkey model of early Alzheimer's DiseaseR21AG064448 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J, MORRISON, JOHN H · 2019 to 2020
$425k
NIA NIH HHS R21 AG064448NIA NIH HHS R21 AG064599NIH HHS P51 OD011107NIH HHS S10 OD030440NIMH NIH HHS R01 MH125411NINDS NIH HHS U54 NS127758
6 · The paper itself

Abstract

introductionThe coppery titi monkey (Plecturocebus cupreus) is an essential nonhuman primate model for social neuroscience, yet neuroimaging studies have been severely constrained by the paucity of standardized atlases. We address this gap by introducing the first MRI-based atlas package for the titi monkey brain that includes a single-subject atlas (UC Davis Titi monkey Neuroimaging Atlas (UCD-TiNA)), alongside a population atlas (UCD-TiNA_group) and a manually-segmented atlas compilation (UCD-TiNA_mac).

methodsUCD-TiNA comprises 74 hierarchically organized regions delineated from the MRI of a representative adult brain, along with whole brain, gray and white matter masks. These segmentations were propagated to the population template (UCD-TiNA_group, N = 17 monkeys) generated to enhance generalizability. A manually-segmented atlas compilation (UCD-TiNA_mac, N = 6 monkeys, 14 regions) was created to enable multi-atlas segmentation approaches. UCD-TiNA and UCD-TiNA_mac were evaluated in a [

resultsThe warped UCD-TiNA achieved a high concordance with the manually-segmented UCD-TiNA_mac labels (median Dice = 0.74). Regional [ DISCUSSION: This work delivers the first in vivo atlas package to enable standardized, reproducible and cross-modal analyses of titi monkey neuroimaging data. By providing a common anatomical reference, this atlas package should facilitate rigorous and harmonized data processing, supporting high-throughput and longitudinal investigations in social neurobiology and informing translational research on social behavior.

Indexed as

Atlases as TopicBrainMagnetic Resonance ImagingNeuroimagingPitheciidaeAnimalsFemaleMalePositron-Emission Tomography[(11)C]GR103545 PETHierarchical brain atlasPopulation templateSocial bondingTiti monkey

Identifiers

PMID41967786
PMCPMC13193678

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.