SynthesisInterdisciplinary cardiovascular and thoracic surgery2026
Perioperative Outcomes of Complex Versus Simple Segmentectomy Via Uniportal Video-Assisted Thoracoscopic Surgery for Lung Lesions: A Systematic Review and Meta-Analysis.
Synthesis in Interdisciplinary cardiovascular and thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesUniportal video-assisted thoracoscopic surgery (U-VATS) has been increasingly adopted for anatomical segmentectomy because of its minimally invasive nature and favourable recovery profile. However, whether perioperative outcomes differ between complex and simple segmentectomy when performed via U-VATS remains uncertain. This study compared perioperative outcomes between complex and simple U-VATS segmentectomy.
methodsA systematic review and meta-analysis were conducted according to PRISMA 2020 and AMSTAR 2 guidelines, and the study was registered in PROSPERO (CRD420251151464). Six databases were searched for studies comparing complex and simple U-VATS segmentectomy for pulmonary lesions. Primary outcomes were operative time, intraoperative blood loss, and conversion to thoracotomy. Secondary outcomes included chest tube duration, hospital stay, and postoperative complications. Random-effects models were used for pooled analyses.
resultsFive retrospective studies, including 1051 patients (707 complex; 344 simple), were analysed. No statistically significant differences were detected in operative time (MD = 15.25 min, 95% CI: -1.25 to 31.75; P = .07; I2 = 88%), intraoperative blood loss (MD = -1.33 mL, 95% CI: -11.95 to 9.29; P = .81; I2 = 58%), or conversion to thoracotomy (OR = 0.46, 95% CI: 0.10-1.99; P = .30; I2 = 0%). Secondary outcomes also showed no significant differences, including chest tube duration (MD = -0.15 days, 95% CI: -0.41 to 0.11; P = .25; I2 = 26%), hospital stay (MD = -0.16 days, 95% CI: -0.73 to 0.40; P = .57; I2 = 66%).
conclusionsNo statistically significant differences were detected in key perioperative outcomes between complex and simple U-VATS segmentectomy; however, given substantial clinical heterogeneity and limited retrospective evidence, findings should be interpreted cautiously and are most applicable to selected patients treated in experienced, high-volume centres.
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