Bronchial Mucosal Abnormalities in Idiopathic Subglottic Stenosis.

Sydney Ring, Andrew Jay Bowen, Tessa Griffin, J Scott Ferguson, Seth H Dailey

Abstract read

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Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sydney RingDepartment of Otorhinolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0009-0004-3955-450X

Andrew Jay BowenMetrohealth Medical Center, Cleveland, Ohio, USA.ORCID 0000-0002-6542-7932

Tessa GriffinDivision of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0009-0007-0081-2972

J Scott FergusonDivision of Allergy, Pulmonary, and Critical Care, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Wisconsin, USA.ORCID 0000-0001-8002-152X

Seth H DaileyDivision of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesInvestigate synchronous lower airway findings during bronchoscopy in idiopathic subglottic stenosis (iSGS).

methodsRetrospective analysis of bronchoscopic images from adult iSGS patients (January 2018-June 2021). Images were reviewed for pits, depressions, nodules, and striations distal to the cricotracheal junction.

resultsForty-eight female patients; mean age 56 years. Comorbidities: gastroesophageal reflux 34%, hypertension 34%, diabetes mellitus 25%. All patients had pits and depressions; striations in 48/48, with both longitudinal and transverse in 32/48 (66.7%), transverse only in 13/48 (27.1%), and longitudinal only in 3/48 (6.3%). Spirometry available in 32; 60% showed normal or mild-moderate fixed obstruction. Four patients had FEV

conclusionBronchial mucosal abnormalities are prevalent in iSGS and may indicate distal airway involvement. Routine flexible bronchoscopy should be considered during evaluation and surveillance. LEVEL OF EVIDENCE: 4:

Indexed as

BronchiLaryngostenosisRespiratory MucosaAdultAgedBronchoscopyFemaleHumansMaleMiddle AgedRetrospective Studiesairway inflammationbronchial diverticulabronchoscopysubglottic stenosis

Identifiers

PMID41966683

DOI10.1002/lary.70543

PMCPMC13357366

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