Evidence map›Paper›PMID 41965871›Full record

ArticleBMC psychology2026

Effectiveness of multi-family group therapy for school refusal in adolescents with depressive disorders: study protocol for a randomized controlled trial.

Yulu Wang, Xuechun Wang, Yixin Xiong, Pengyu Zhan, Ruoxi Ding, Chuan Shi

Abstract readClinical Trial Protocol
In one paragraph

Article in BMC psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yulu WangPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
Xuechun WangPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
Yixin XiongPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
Pengyu ZhanPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China.
Ruoxi DingPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China. dingruoxi@163.com.
Chuan ShiPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, China. shichuan@bjmu.edu.cn.

Funding

Beijing Research Ward Excellence Program BRWEP 2024W074110119
6 · The paper itself

Abstract

objectiveThis study aims to develop a manualized multi-family group therapy (MFGT) program for adolescents with depressive school refusal and to evaluate its effectiveness through a randomized controlled trial. By comparing MFGT with group cognitive behavioral therapy (GCBT), the study seeks to examine the relative efficacy of MFGT in improving school refusal behaviors and depressive symptoms, to assess the stability of treatment effects during follow-up, and to explore potential mechanisms underlying behavioral change.

methodsThis study is designed as a single-center, single-blind, randomized controlled non-inferiority trial. A total of 138 adolescents aged 12-19 years who meet DSM-5 criteria for depressive disorders and Berg’s criteria for school refusal will be randomly assigned in a 1:1 ratio to either the MFGT plus treatment-as-usual (TAU) group or the GCBT plus TAU group. Both interventions consist of eight group sessions delivered over four weeks. Primary outcomes include school attendance rate and clinician-rated depressive symptoms assessed using the Hamilton Depression Rating Scale. Secondary and intermediate outcomes include self-reported depressive and anxiety symptoms, school refusal maintaining factors, school-related self-efficacy, family functioning, and parent–adolescent communication. Assessments will be conducted at baseline, post-treatment, and at 1- and 3-month follow-up. DISCUSSION: This study will be the first randomized controlled trial to evaluate a standardized and manualized MFGT protocol specifically developed for adolescents with depressive school refusal. By adopting a family-based and scalable intervention model, the study is expected to provide evidence for an effective and resource-efficient treatment approach that addresses both individual psychopathology and family dynamics. The findings may contribute to improving school attendance and mental health outcomes in adolescents and inform clinical practice and public mental health strategies in settings with limited mental health resources.

trial registrationChinese Clinical Trial Registry (ChiCTR2500100225). Registered, 2025.

Indexed as

Cognitive Behavioral TherapyDepressive DisorderFamily TherapyPsychotherapy, GroupAdolescentChildEquivalence Trials as TopicFemaleHumansMaleRandomized Controlled Trials as TopicSchoolsSingle-Blind MethodYoung AdultAdolescentDepressive disordersMulti-family group therapyRandomized controlled trialSchool refusalStudy protocol

Identifiers

PMID41965871
PMCPMC13267200

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.