ArticleBMC research notes2026
Positive correlation between IL-6 levels and lumbar bone mineral density in menopausal women diagnosed with osteoporosis in comparison to menopausal women without osteoporosis.
Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoporosis is a common bone disorder characterized by decreased bone density. Interleukin-6 (IL-6), plays a crucial role in bone homeostasis. This study aimed to evaluate the relationship between serum levels of IL-6 and lumbar bone marrow density (LBMD) in postmenopausal women with osteoporosis compared to those without the condition. In addition we investigated the level of PTH, ALP, Ca, FSH and LH in case and control and compared them between two groups. MATERIALS AND
methodsIn this study, 5cc of blood was collected from 60 participants (case and control) without anticoagulant. Serum was separated and stored at -20 °C. ALP and calcium (Ca) were measured using a colorimetric method, while PTH, LH, and FSH levels were assessed by enzyme-linked immunosorbent assay (ELISA). The results were analyzed by SPSS version 18, with a significance level set at p < 0.05.
resultsOur findings showed the serum level of IL-6 increased significantly in postmenopausal women with osteoporosis compared to the control group (p-value = 0.001). Serum levels of LH, FSH, ALP, and PTH in both groups were not statistically different (p-value = 0.089). Additionally, we found a positive correlation between BMD Lumbar with IL-6 in menopausal women with osteoporosis.
conclusionOur findings illustrated the positive correlation between lumbar spine BMD with IL-6, FSH, ALP, and Ca in MPO women, while hip BMD positively correlated with IL-6, PTH, and FSH serum levels. The correlations between various factors were not statistically significant, except for the relationship between BMD in the lumbar spine and IL-6 levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.