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ArticleAnnals of biomedical engineering2026

Additively Manufactured Patient-Specific Trabecular Bone Imitations in Anatomical Bone Models for Preoperative Planning and Surgical Training: A Manufacturing Framework.

Maximilian Pestel, Gerhard Martin Hobusch, Jürgen Alphonsus, Gregor Wollner, Madeleine Willegger, Andreas Strassl, Iris-Melanie Noebauer-Huhmann, Reinhard Windhager, Maximilian Lackner, Emir Benca

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Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Maximilian PestelDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. maximilian.pestel@meduniwien.ac.at.ORCID http://orcid.org/0009-0006-0824-6701
Gerhard Martin HobuschDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Jürgen AlphonsusDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Gregor WollnerDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Madeleine WilleggerDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Andreas StrasslDepartment of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Iris-Melanie Noebauer-HuhmannDepartment of Biomedical Imaging and Image‑guided Therapy, Division of Neuroradiology and Musculoskeletal Radiology, Medical University of Vienna, Währinger Gürtel 18‑20, 1090, Vienna, Austria.
Reinhard WindhagerDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Maximilian LacknerPolymer Institute SAS, Slovak Academy of Sciences, Dúbravská cesta 9, 45, 845 41, Bratislava, Slovakia.
Emir BencaDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdditively manufactured (3D-printed) anatomical bone models are used for medical education and surgical training. Manufacturing of patient-specific anatomies and rare pathologies has improved rapidly in the recent past, enabling training opportunities that were previously restricted to limitedly available anatomic specimens. However, the imitation of patient-specific trabecular bone in additively manufactured bone models remains complex and thus inadequately addressed.

methodsTest specimens in the form of Gyroid and Voronoi lattice cubes were manufactured via fused filament fabrication (FFF)-printing at varying densities with polylactide, polylactide /carbon fiber composite and polyamide /glass fiber composite filaments, and submerged in gelatin. Additionally, trabecular bone test cubes were removed from bovine femoral specimens, and the bone mineral density (BMD) was assessed utilizing quantitative computed-tomography (QCT). Subsequently, haptic drill resistance of all test cubes was evaluated by four orthopedic and trauma surgeons, and the mechanical drill resistance was assessed using a load frame.

resultsMultiple polymer lattice structures and material configurations were evaluated by the surgeons as suitable to mimic actual trabecular bone (Likert ratings between 2.60 and 3.00). Regression analyses of the surgeons' evaluations of both the trabecular bone (R

conclusionThe imitation of trabecular bone models via FFF-printing is feasible and could substantially enhance the haptic feedback in additively manufactured anatomical bone models. Applying the presented manufacturing framework enables the cost- and time-efficient production of patient-specific anatomical models to enhance preoperative planning and surgical training.

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3D-printingAnatomical modelsBoneDrill resistanceMedical educationSurgical training

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.