Evidence map›Paper›PMID 41965420›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Beyond sacral slope: a new quantitative paradigm for Roussouly classification.

Domenico Compagnone, Andrea Pezzi, Francesca Barile, Francesco Langella, Riccardo Cecchinato, Luca La Verde, Marco Damilano, Daniele Vanni, Andrea Redaelli, Luca Maria Sconfienza and 2 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Domenico CompagnoneIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Andrea PezziUniversity of Milan, Milan, Italy.
Francesca BarileIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Francesco LangellaIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy. francesco.langella.md@gmail.com.
Riccardo CecchinatoIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Luca La VerdeASST Gaetano Pini-CTO, Milan, Italy.
Marco DamilanoIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Daniele VanniIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Andrea RedaelliIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Luca Maria SconfienzaIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Claudio LamartinaIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.
Pedro BerjanoIRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo propose a pelvic incidence (PI)-based asymptomatic spine classification, quantitatively define differences among Roussouly morphotypes, and develop a morphotype-oriented algorithm to guide surgical planning.

methodsA retrospective analysis of 102 asymptomatic adults undergoing full-spine EOS radiographs was performed. Patients were classified according to the original Roussouly criteria. Spinopelvic parameters were measured using validated software. Receiver operating characteristic (ROC) curve analysis assessed the discriminative capacity of sagittal variables, with optimal cutoffs determined using the Youden index. A one-versus-rest ROC approach was applied for three-group comparisons. Linear regression analysis evaluated the relationship between lumbar lordosis (LL), PI, and Roussouly type.

resultsAlthough mean PI increased across types, significant overlap was observed among Types 1-3 for PI < 50°. In the binary comparison between Types 1 and 2, L5-S1 lordosis showed the highest discriminative performance (AUC 0.92; 95% CI 0.848-0.997; p < 0.001), with a cutoff of 19° differentiating Type 2 (≤ 19°) from Type 1 (> 19°). In the three-group analysis (Types 1-3), L5-S1 remained the most discriminative parameter (Type 2 vs. rest AUC 0.85). Thoracolumbar junction morphology differed consistently: kyphotic in Type 1, neutral in Type 2, and neutral-to-lordotic in Type 3.

conclusionSagittal alignment cannot be defined by PI alone. Integration of distal lordosis (L5-S1) and thoracolumbar morphology improves morphotype differentiation and may support more precise surgical planning.

Indexed as

Adult spine deformityLumbar lordosisRoussouly classificationSagittal balanceSpinopelvic alignmentSurgical planning

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.