Evidence map›Paper›PMID 41965336›Full record

ReviewNature communications2026

Transforming healthcare through in-body bioelectronic systems.

Steven Ceto, Stacey Amanda Elshove, Mingzheng Wu, Khalil Ramadi, Christoph Tondera, Ivan Rusev Minev, Shriya Srinivasan, Kyuhwa Lee, Michalina J Gora, John Rogers and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biointegrated Battery-Based Electroceuticals.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Steven CetoWyss Center for Bio and Neuroengineering, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-0101-3685
Stacey Amanda ElshoveDepartment of Fundamental Neurosciences, University of Lausanne (UNIL), Lausanne, Switzerland.ORCID http://orcid.org/0009-0007-0402-181X
Mingzheng WuQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL, USA.ORCID http://orcid.org/0000-0003-4415-6296
Khalil RamadiDivision of Engineering, New York University Abu Dhabi, Abu Dhabi, UAE.
Christoph TonderaInstitute of Biofunctional Polymer Materials, Leibniz Institute of Polymer Research Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-4485-8143
Ivan Rusev MinevInstitute of Biofunctional Polymer Materials, Leibniz Institute of Polymer Research Dresden, Dresden, Germany.
Shriya SrinivasanDivision of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Kyuhwa LeeWyss Center for Bio and Neuroengineering, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-3854-4690
Michalina J GoraWyss Center for Bio and Neuroengineering, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-1200-3511
John RogersQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL, USA.ORCID http://orcid.org/0000-0002-2980-3961
Claudia KatheDepartment of Fundamental Neurosciences, University of Lausanne (UNIL), Lausanne, Switzerland. claudia.kathe@unil.ch.ORCID http://orcid.org/0000-0001-6441-1755
Thomas Haynes HutsonWyss Center for Bio and Neuroengineering, Geneva, Switzerland. thomas.hutson@wysscenter.ch.ORCID http://orcid.org/0000-0001-6795-2688

Funding

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 853378International Foundation for Research in Paraplegia (Internationale Stiftung für Forschung in Paraplegie) P205Novartis Foundation 24B094Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 10006212Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 218058
6 · The paper itself

Abstract

Recent advances in the development of in-body bioelectronic systems are providing new opportunities for the clinical management of various diseases and disorders. These emerging technologies are tailored to specific organs and are beginning to blend both diagnostic sensing and therapeutic actuation. The aim of these systems is to seamlessly integrate with the physiological environment, as illustrated by the diverse device strategies discussed throughout this article. Next generation modalities, such as optogenetics combining gene therapy with devices for photostimulation, are gaining popularity and offer advantages over existing therapeutic strategies. In this perspective, we explore the current state of technological developments, key challenges in the field and potential pathways for translating these innovations into clinical practice.

Indexed as

Delivery of Health CareElectronics, MedicalAnimalsBiosensing TechniquesGenetic TherapyHumansOptogenetics

Identifiers

PMID41965336
PMCPMC13076800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.