Evidence map›Paper›PMID 41965169›Full record

ArticleMedical image analysis2026

Neural implicit heart coordinates: 3D cardiac shape reconstruction from sparse segmentations.

Marica Muffoletto, Uxio Hermida, Charlène A Mauger, Avan Suinesiaputra, Yiyang Xu, Richard Burns, Lisa Pankewitz, Andrew D McCulloch, Steffen E Petersen, Daniel Rueckert and 1 more

Abstract read
In one paragraph

Article in Medical image analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Marica MuffolettoSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK. Electronic address: marica.muffoletto@kcl.ac.uk.
Uxio HermidaSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Charlène A MaugerSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Avan SuinesiaputraSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Yiyang XuSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Richard BurnsWilliam Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University, London, UK.
Lisa PankewitzSimula Research Laboratory, Oslo, Norway; Department of Informatics, University of Oslo, Oslo, Norway.
Andrew D McCullochDepartment of Bioengineering, University of California,San Diego, USA.
Steffen E PetersenWilliam Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University, London, UK; Barts Heart Centre, Barts Health NHS Trust, St Bartholomew's Hospital, West Smith, London, UK.
Daniel RueckertTechnical University of Munich, Munich, Germany.
Alistair A YoungSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Funding

The Cardiac Atlas ProjectR01HL121754 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCULLOCH, ANDREW D., OMENS, JEFFREY H. · 2014 to 2023
$5.0M
NHLBI NIH HHS R01 HL121754UK Biobank 2964Wellcome Trust
6 · The paper itself

Abstract

Accurate reconstruction of cardiac anatomy from sparse clinical images remains a major challenge in patient-specific modeling. While neural implicit functions have previously been applied to this task, their application to mapping anatomical consistency across subjects has been limited. In this work, we introduce Neural Implicit Heart Coordinates (NIHCs), a standardized implicit coordinate system, based on universal ventricular coordinates, that provides a common anatomical reference frame for the human heart. Our method predicts NIHCs directly from a limited number of 2D segmentations (sparse acquisition) and subsequently decodes them into dense 3D segmentations and high-resolution meshes at arbitrary output resolution. Trained on a large dataset of 5000 cardiac meshes, the model achieves high reconstruction accuracy on clinical contours, with mean Euclidean surface errors of 2.51 ± 0.33 mm in a diseased cohort (n=4549) and 2.31 ± 0.36 mm in a healthy cohort (n=5576). The NIHC representation enables anatomically coherent reconstruction even under severe slice sparsity and segmentation noise, faithfully recovering complex structures such as the valve planes. Compared with traditional pipelines, inference time is reduced from over 60 s to 5-15 s. These results demonstrate that NIHCs constitute a robust and efficient anatomical representation for patient-specific 3D cardiac reconstruction from minimal input data. The code is available at https://github.com/marsof97/NIHC.

Indexed as

HeartImaging, Three-DimensionalAlgorithmsHumans3D mesh reconstructionCardiac imagingNeural implicit functionsUniversal ventricular coordinates

Identifiers

PMID41965169
PMCPMC13594572

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.