Evidence map›Paper›PMID 41964831›Full record

Observational studyInternational urology and nephrology2026

Telemedicine-supported assisted home hemodialysis in elderly and multimorbid patients: a real-world cohort study in a public healthcare system.

Anna Zito, Paolo Ria, Maria Luisa Lefons, Vilma Martella, Silvia Matino, Giulia Fontò, Silvia Barbarini, Tiziana Rollo, Marcello Napoli, Antonio De Pascalis

Abstract readObservational Study
In one paragraph

Observational study in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Anna ZitoDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy. anna.zito@unisalento.it.ORCID http://orcid.org/0000-0002-1377-6137
Paolo RiaDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Maria Luisa LefonsDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Vilma MartellaDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Silvia MatinoDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Giulia FontòDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Silvia BarbariniDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Tiziana RolloDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Marcello NapoliDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.
Antonio De PascalisDepartment of Nephrology, Dialysis and Transplantation, Vito Fazzi Hospital, ASL Lecce, Lecce, Italy.ORCID http://orcid.org/0000-0003-1685-7263

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aging of the hemodialysis (HD) population and the growing burden of multimorbidity increasingly challenge the sustainability and equity of conventional in-center dialysis within publicly funded healthcare systems. Although home hemodialysis (HHD) may offer clinical and organizational advantages, its implementation remains limited among elderly and functionally dependent patients. We evaluated the real-world feasibility, retention, and system-level impact of a telemedicine-supported assisted-HHD (A-HHD) program aimed at broadening access to complex individuals. We performed a retrospective, descriptive observational cohort study including all patients enrolled in an A-HHD program within a public healthcare authority in Southern Italy from June 2018 to June 2025. In September 2023, a structured telemedicine platform enabling real-time remote monitoring and audiovisual supervision was integrated into routine care. We assessed epidemiological trends, patient complexity, vascular access patterns, dialysis prescription and delivered dose, treatment retention, causes of discontinuation, and transportation-related economic outcomes.

resultsA total of 146 patients (mean age 79 ± 7 years) with substantial cardiovascular, metabolic, and respiratory comorbidity were treated. Central venous catheters were used in 64% of cases. Following early program expansion, annual incidence stabilized at approximately 20-25 patients, while prevalence steadily increased, exceeding 20 active patients per month. More than half of patients remained on therapy beyond 6 months. Despite shorter individual sessions, increased treatment frequency achieved a weekly standard Kt/V comparable to conventional in-center HD. Treatment discontinuation was predominantly related to mortality or clinical indications rather than program failure.

conclusionTelemedicine-supported A-HHD represents a feasible and organizationally sustainable model capable of expanding equitable access to home-based dialysis while supporting organizational sustainability in public healthcare systems.

Indexed as

Hemodialysis, HomeKidney Failure, ChronicTelemedicineAgedAged, 80 and overCohort StudiesFemaleHumansItalyMaleMultimorbidityRetrospective StudiesAging populationDelivery of health careFrailtyHealth care costsHome hemodialysisPublic health systemsRenal dialysisTelemedicine

Identifiers

PMID41964831
PMCPMC13585893

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.