ArticleWorld journal of urology2026
Predictive value of systemic immune-inflammation index and systemic inflammation response index for orchiectomy risk in patients with testicular torsion.
Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate the predictive value of systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) for orchiectomy risk in patients with testicular torsion.
methodsPatients diagnosed with testicular torsion (TT) and hospitalized for treatment between September 2014 and September 2022 were retrospectively included in this study. Demographic and clinical characteristics were collected and analyzed. Stepwise logistic regression analysis was applied to identify independent predictors of orchiectomy risk. The predictive performance of the model incorporating SII and SIRI was evaluated using receiver operating characteristic (ROC) curve and decision curve analysis (DCA).
results122 patients undergoing orchiopexy and 61 patients undergoing orchiectomy were included in this study. The final multivariate logistic regression analysis showed that duration of torsion (p < 0.001, OR = 1.036), degree of twisting (p = 0.022, OR = 1.0029), age (p = 0.02, OR = 0.909), SII (p = 0.006, OR = 0.9989), SIRI (p = 0.006, OR = 1.282), and successful manual detorsion (p = 0.01, OR = 0.019) were independently associated with orchiectomy risk. The model incorporating SII and SIRI achieved slightly higher AUC and showed improved clinical net benefit on DCA.
conclusionsSystemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) demonstrate potential predictive value for orchiectomy risk in patients with testicular torsion.
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