ArticleJACC. Case reports2026
Early Healing After Left Atrial Appendage Occlusion Confirmed by Surgical Explantation.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
backgroundHealing of left atrial appendage (LAA) occlusion devices is believed to occur over several months; however, direct histological confirmation in humans remains limited. CASE SUMMARY: An elderly patient underwent LAA occlusion and subsequently required total arch replacement 3 months later because of progressive aortic pathology. The device had previously been noted to have suboptimal positioning. Surgical explantation provided a rare opportunity for direct tissue evaluation. Histological examination demonstrated fibrous tissue coverage over the portion of the device in contact with the LAA wall, whereas the atrial-facing filter surface showed no tissue coverage. DISCUSSION: This case provides rare direct histological evidence of early fibrous tissue coverage after LAA occlusion and offers unique insight into the biological healing process after device implantation. TAKE-HOME MESSAGE: Early fibrous coverage after LAA occlusion may occur within 3 months, as demonstrated by surgical explantation.
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