Evidence map›Paper›PMID 41964602›Full record

ArticleJournal of studies on alcohol and drugs2026

E-Cigarette Use Trajectories and Respiratory Symptoms in Adolescents and Young Adults: Sustained Use Linked to Greater Symptom Frequency.

Abigail Shores, Hannah Appleseth, Ruochen Zhao, Megan E Roberts, Bo Lu, Jill M Singer, Dylan Wagner, Elizabeth G Klein, Loren E Wold, Marielle C Brinkman and 2 more

Abstract read
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In one paragraph

Article in Journal of studies on alcohol and drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Abigail ShoresCollege of Public Health, The Ohio State University, Columbus, Ohio, USA.
Hannah ApplesethDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
Ruochen ZhaoCenter for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Megan E RobertsCollege of Public Health, The Ohio State University, Columbus, Ohio, USA.
Bo LuCollege of Public Health, The Ohio State University, Columbus, Ohio, USA.
Jill M SingerCollege of Public Health, The Ohio State University, Columbus, Ohio, USA.
Dylan WagnerDepartment of Psychology, The Ohio State University, Columbus, Ohio, USA.
Elizabeth G KleinCollege of Public Health, The Ohio State University, Columbus, Ohio, USA.
Loren E WoldDepartment of Surgery, The Ohio State University, Columbus, Ohio, USA.
Marielle C BrinkmanCollege of Public Health, The Ohio State University, Columbus, Ohio, USA.
Theodore L WagenerCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Alayna P TackettCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.

Funding

Respiratory effects of E-Cigarette use among Youth: A prospective, longitudinal investigationK01HL148907 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TACKETT, ALAYNA PAULINE · 2019 to 2023
$981k
NHLBI NIH HHS K01 HL148907
6 · The paper itself

Abstract

objectiveThis study cross-sequentially examined three measures of self-reported respiratory symptoms and nicotine e-cigarettes (EC) use adjusting for past 30-day use of cannabis/tobacco, COVID-19, and lifetime asthma at baseline (T1) and 12-months (T2).

methodData came from the Emerging Adulthood Health Project. AYAs aged 15-24 (N= 751) self-reported demographics, nicotine/cannabis use, and respiratory symptoms. EC use at T1-T2 was categorized into a) never use, b) non-escalating, c) increasing, or d) sustained use. Binary and linear logistic regressions examined outcomes at T2.

resultsAt T1, participants (M age= 20.56 years [SD= 2.09 years]) were mostly female (n= 423 [56.6%]), White (n= 563 [75.3%]), and college students (n= 510 [68.0%]). In unadjusted analyses, EC sustained use had a significantly higher number of summed symptoms (binary; OR= 1.47, 95% CI [1.04, 2.07], p= .03) and more days with symptoms (OR= 1.64, 95% CI [1.16, 2.32], p= .006) compared to never EC use. In adjusted analyses, sustained EC use had higher American Thoracic Society Questionnaire scores (b=1.48, SE= 0.54, p=.0006) than never EC use, but the number of summed symptoms and days with symptoms became non-significant. Among participants experiencing any day with symptoms (N= 269), sustained (b= 2.05, SE=0.95, p=.03) and non-escalating use (b= 2.73, SE= 1.17, p= .02) was associated with more days with symptoms than never EC use in adjusted analyses.

conclusionsEC use behavior impacts self-reported frequency of respiratory symptoms among AYAs, with those who continue to use reporting more frequent symptoms, after adjusting for tobacco/cannabis use, COVID-19, and asthma.

Identifiers

PMID41964602
PMCPMC13094720

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