ReviewMedical gas research2026
Hyperbaric oxygen therapy for knee osteoarthritis: treatment mechanism, potential advantages, and limitations.
Review in Medical gas research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Knee osteoarthritis is a common chronic joint disease. Although there are many treatment options available for knee osteoarthritis, most focus on alleviating symptoms rather than halting disease progression, repairing cartilage, reversing joint damage, or restoring the structure and function of the knee. Hyperbaric oxygen therapy works by increasing tissue oxygen concentrations by increasing higher atmospheric pressure. This therapy can directly improve the hypoxic microenvironment in knee osteoarthritis. Hyperbaric oxygen therapy can also improve oxygenation, reduce oxidative stress and regulate inflammatory responses. In addition, it plays an important role in promoting angiogenesis, cartilage repair and regeneration, and healing of damaged joint tissue. This review explores the therapeutic effect of hyperbaric oxygen therapy on knee osteoarthritis, systematically analyzes its therapeutic mechanism, potential advantages and current limitations, and provides direction for future research. As it continues to develop, hyperbaric oxygen therapy has the potential to become a non-invasive, efficient and highly targeted treatment option, bringing new hope to patients with knee osteoarthritis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.