ArticleJournal of cardiovascular electrophysiology2026
Clinical Prediction Model for Unsuccessful Left Bundle Branch Area Pacing.
Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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14 authors.
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Abstract
introductionLeft bundle branch area pacing (LBBAP) has rapidly become a preferred form of cardiac physiologic pacing; however, predictors of unsuccessful implantation remain unclear. METHODS AND
resultsBetween April 2020 and March 2024, LBBAP was attempted in 145 patients. Procedural success was defined by ≥ 1 of the following: output-dependent QRS morphology changes, V6 R-wave peak time (RWPT) < 75 ms, V6-V1 interpeak interval ≥ 44 ms, or concordance between intrinsic and paced V6 RWPT derived from left bundle potentials. Baseline clinical, electrocardiographic, and echocardiographic variables were compared between success (n = 126, 86.9%) and failure (n = 19, 13.1%) groups. Multivariable logistic regression using Firth's penalized likelihood identified nonspecific intraventricular conduction delay (NIVCD) (odds ratio [OR] = 4.34; p = 0.02), interventricular septal thickness (IVSd) (OR = 1.39 per mm; p = 0.03), and right atrial area (RAA) (OR = 1.12 per cm
conclusionNIVCD, septal hypertrophy, and right atrial enlargement are independent predictors of LBBAP failure. The resulting validated prediction model and nomogram provide individualized pre-procedural risk estimation and may assist in optimizing patient selection and procedural strategy.
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