Evidence map›Paper›PMID 41964495›Full record

ArticlePediatric blood & cancer2026

A High-Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK-Rearranged Non-Small Cell Lung Cancer.

Alberto D Guerra, Nicholas F Evageliou, Vandana Batra, Kristen L Dalton, Stephanie Ortel, Usman Ashraf, Tricia R Bhatti, Lisa J States, Lea F Surrey, Theodore W Laetsch

Abstract readLetter
In one paragraph

Article in Pediatric blood & cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alberto D GuerraDivision of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0009-0008-6789-2652
Nicholas F EvageliouDivision of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-5567-0007
Vandana BatraDivision of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-2963-4835
Kristen L DaltonDivision of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Stephanie OrtelDivision of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Usman AshrafCaris Life Sciences, Irving, Texas, USA.
Tricia R BhattiDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lisa J StatesDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lea F SurreyDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6944-2232
Theodore W LaetschDivision of Oncology and Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-8497-3138

Funding

Rare Tumor Clinical Research SpecialistR50CA305079 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI Theodore Willis Laetsch · 2025 to 2026
$395k
Alex's Lemonade Stand Foundation Center of Excellence and NIH 1R50CA305079NCI NIH HHS R50 CA305079NIH HHS 2T32CA009615
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alectinibcirculating nucleic acid sequencingcirculating tumor DNAliquid biopsypediatric non–small cell lung cancer

Identifiers

PMID41964495
PMCPMC13340761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.