ArticleOrthodontics & craniofacial research2026
Enhancement of Orthodontic Tooth Movement by Oral Administration of Pangasius hypophthalmus Oil: An In Vivo Study.
Article in Orthodontics & craniofacial research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundEnhancing orthodontic tooth movement is a crucial aspect in reducing the duration of treatment. This study aims to investigate the potential of Pangasius hypophthalmus oil in promoting tooth movement in rabbits. MATERIALS AND
methodsForty-eight male rabbits were employed in four experimental groups (n = 12 per group): Group 1 served as the control, while Groups 2, 3, and 4 received oral doses of Pangasius hypophthalmus oil at concentrations of 250 mg/kg body weight, 500 mg/kg body weight, and 1,000 mg/kg body weight, respectively. Orthodontic appliances were placed between the lower central incisors of the rabbits, applying an orthodontic force of 100 g/mm
resultsThe administration of Pangasius hypophthalmus oil with a dose of 1,000 mg/kg body weight led to the highest increase of orthodontic movement, indicated by a rise of TRAP and OPN expression compared to other concentrations (p < 0.05).
conclusionThe Pangasius hypophthalmus oil has the potent ability to increase the orthodontic tooth movement, indicated by the rise in TRAP and OPN expression.
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