ArticleZoonoses and public health2026
Interventions Targeting the Beef Feedlot Environment to Control Antimicrobial Resistance: A Mathematical Modelling Study.
Article in Zoonoses and public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionTo address concerns about livestock as a source of antimicrobial-resistant bacteria and genes, there have been many recent efforts worldwide to study prescribing practices, optimal antibiotic use, and alternatives to antibiotic use. However, there is empirical evidence supporting the persistence of antimicrobial resistance genes at high densities in cattle pens for at least 2 years after cattle were removed.
methodsWe describe a mathematical modelling framework to predict and explore the dynamics of antimicrobial-resistant enteric bacteria in food-producing animals and their immediate environments. Using the difference equation based compartmental modelling framework, we algebraically derive a formula for the relative rate of growth of antimicrobial-resistant enteric bacteria in the environment (R
resultsWe demonstrate that R
conclusionsFarm environments such as beef cattle feedlots may be conducive to persistence or even growth of antimicrobial resistant bacteria under a wide range of plausible conditions, even in the absence of antimicrobial use. The system may be quite resilient, and even stringent cleaning will likely not be sufficient to eliminate resistant bacteria from the environment in some climates, especially where freeze-thaw cycles are uncommon.
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