Trial reportJournal of neuroengineering and rehabilitation2026
Unlocking trunk potential after stroke: a novel approach combining transcranial direct current stimulation and core stability exercise: a randomized controlled trial.
Trial report in Journal of neuroengineering and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06882213 (Unlocking Trunk Potential After Stroke), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Unlocking Trunk Potential After Stroke: A Novel Approach Combining Transcranial Direct Current Stimulation and Core Stability Exercise
Who cites it
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImpaired trunk control is a critical contributor to poststroke disability, as it undermines balance, mobility, and independence. Core stability exercises (CSEs) improve trunk function; however, their efficacy may be limited by post-stroke reductions in cortical excitability. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that enhances neuroplasticity and may potentiate the effects of rehabilitation.
objectiveTo determine whether combining tDCS with CSEs improves trunk control, balance, and functional independence in chronic stroke survivors.
methodsIn this single-blind randomized controlled trial, 60 participants with post-stroke hemiparesis were assigned to either a study group (n = 30) receiving anodal tDCS (2 mA, 20 min) over the ipsilesional primary motor cortex concurrent with CSEs or a control group (n = 30) receiving CSEs alone. Both groups underwent supervised sessions three times per week for 12 weeks. The primary outcome was the Trunk Impairment Scale (TIS). Secondary outcomes included the Postural Assessment Scale for Stroke (PASS), Berg Balance Scale (BBS), and Barthel Index (BI).
resultsBoth groups improved significantly across all the outcomes (p < 0.001). The combined intervention produced greater gains than did CSE alone: TIS (+ 2.80 vs. +1.83, p = 0.005), PASS (+ 4.01 vs. +1.31, p = 0.001), BBS (+ 6.64 vs. +2.21, p < 0.001), and BI (+ 9.20 vs. +1.96, p < 0.001). Trunk improvements strongly predicted functional gains (ΔTIS vs. ΔBI, r = 0.72, p < 0.001).
conclusionSimultaneous tDCS and CSEs significantly enhance trunk control, balance, and independence beyond the benefits of exercise alone, representing a promising strategy for post-stroke neurorehabilitation. Trial registration The trial was registered at ClinicalTrials.gov (Identifier: NCT06882213; registered on 12 March 2025). This study was retrospectively registered.
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