Evidence map›Paper›PMID 41964035›Full record

ArticlePilot and feasibility studies2026

Pilot study of the DeStress for Health Program: a community-engaged stress reduction and cancer prevention intervention for rural communities.

Devon Noonan, Amnazo Muhirwa, Elaine Sang, Nicole Calhoun, Ardis Crews, Kellen Peter, Henry Crews, Lucette Mercer, Lisa Macon Harrison, Shauna L Guthrie and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Pilot and feasibility studies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03776890 (DeStress for Health), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03776890 nacompletednot on this map

DeStress for Health: Partnering With Granville and Vance Counties to Reduce Stress and Cancer Risk

TypeinterventionalSponsorDuke UniversityRan2019 to 2020Enrolled29ConditionsStress ReductionArmsDeStress for Health Program
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Devon NoonanDuke University School of Nursing, 307 Trent Drive, Durham, NC, 27710, USA. Devon.noonan@duke.edu.ORCID http://orcid.org/0000-0001-6675-8736
Amnazo MuhirwaDuke University School of Nursing, 307 Trent Drive, Durham, NC, 27710, USA.
Elaine SangUniversity of Pennsylvania School of Nursing, 418 Curie Blvd, Philadelphia, PA, 19104, USA.
Nicole CalhounDuke University School of Nursing, 307 Trent Drive, Durham, NC, 27710, USA.
Ardis CrewsGreen Rural Redevelopment Organization, 421 S Garnett St, Henderson, NC, 27536, USA.
Kellen PeterDuke University Hospital, 2301 Erwin Rd, Durham, NC, 27710, USA.
Henry CrewsGreen Rural Redevelopment Organization, 421 S Garnett St, Henderson, NC, 27536, USA.
Lucette MercerGreen Rural Redevelopment Organization, 421 S Garnett St, Henderson, NC, 27536, USA.
Lisa Macon HarrisonGranville Vance Public Health, 101 Hunt Dr, Oxford, NC, 27565, USA.
Shauna L GuthrieGranville Vance Public Health, 101 Hunt Dr, Oxford, NC, 27565, USA.
Kathryn I PollakCancer Control and Population Sciences, Duke Cancer Institute, Department of Population Health Sciences, Duke University School of Medicine, 215 Morris Street, Durham, NC, 27701, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStress related to personal, social, and environmental factors has been linked to engaging in unhealthy behaviors. These behaviors may increase cancer risk. Most current prevention programs do not address stress related to social factors and related stresses that are driving unhealthy behaviors. The purpose of this study was to pilot the DeStress for Heath Program.

methodsWe conducted a pilot randomized controlled trial. Community members from two rural counties were randomized to the DeStress for Health Program group or a waitlist control group. The DeStress for Health Program, developed using a community engaged approach, is a 4-class, in-person, nurse delivered evidenced-based intervention that uses both positive psychology and health behaviour goal setting to address stress reduction and cancer risk behaviours. We offered the program to the waitlist control group after completion of all assessments. Self-report surveys were completed at baseline and 30 days post-intervention in the DeStress arm to assess feasibility and acceptability and 30 days post 4-week wait time in the control. Study outcomes for feasibility included recruitment, retention, and engagement, and acceptability included positive endorsement of the intervention and changes in stress and health behaviours.

resultsWe recruited 29 participants in 6 months, missing our feasibility recruitment benchmark. We did not meet our feasibility benchmark of having 75% of participants attend all 4 classes, with 69% of residents attended at least 2 classes. We retained 21 of 29 (72%) participants at follow-up. Acceptability results include the DeStress group reported that the intervention reduced daily stress (n = 13, 81.3%), helped encourage better nutrition (n = 15, 93.8%) and physical activity (n = 15, 93.8%), and would recommend the program to a friend (n = 15, 93.8%). DeStress improved scores on the Perceived Stress Scale over time compared to the waitlist control. DISCUSSION: The DeStress intervention is acceptable and demonstrates improvements in stress. Feasibility benchmarks were not all met, and suggestions for future adaptations to improve feasibility are discussed. DeStress underscores the importance of developing programs that address real community needs and linking intervention programs with community resources, particularly in rural communities where health-related resources can be scarce.

trial registrationClinicalTrials.gov identifier: NCT03776890.

Indexed as

Cancer riskInterventionRisk behavioursRuralStress

Identifiers

PMID41964035
PMCPMC13188702

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.