ReviewJournal of medical case reports2026
Severe baclofen intoxication managed with hemodialysis: a case report and review of the literature.
Review in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundBaclofen, a γ-aminobutyric acid-B (GABA CASE PRESENTATION: We report the case of a 16-year-old Moroccan female who developed coma and respiratory depression following a suspected baclofen overdose, with an estimated ingestion of 300 mg. She required endotracheal intubation and mechanical ventilation. Due to profound coma with respiratory depression, hemodialysis was initiated in addition to supportive care, despite preserved renal function and the unavailability of baclofen measurements. Neurological recovery occurred gradually over 72 h without apparent long-term complications.
conclusionsThis case underscores the importance of recognizing baclofen toxicity and prioritizing supportive care consistent with the Extracorporeal Treatments In Poisoning (EXTRIP) Workgroup recommendations against routine hemodialysis in preserved renal function. Although hemodialysis was instituted due to profound presentation, its efficacy is unproven, and recovery is attributable to spontaneous clearance rather than dialytic effect.
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