Observational studyBMC geriatrics2026
The association between the geriatric nutritional risk index (GNRI) and postoperative outcomes after hip fracture in older adults: a prospective cohort study.
Observational study in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03184896 (Multicenter Prospective Observational Study in Hip Fracture Among Older Adults), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Multicenter Prospective Observational Study in Hip Fracture Among Older Adults
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8 authors.
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Abstract
backgroundThe GNRI is an objective nutritional status screening tool. This study aimed to investigate the prognostic value of GNRI in predicting long-term outcomes of geriatric hip fracture patients.
methodsWe prospectively enrolled patients aged ≥ 65 years who underwent hip fracture surgery between November 2018 and November 2019. Admission GNRI was categorized into quartiles (Q1 ≤ 96, Q2 96–101, Q3 101–104, Q4 > 104). Patients were followed up at 30 days, 120 days, 1 year and 3 years postoperatively. Cox proportional hazards model and ROC curve were performed to evaluate mortality risk; multiple logistic regression identified the value for recovery of pre-fracture mobility. Multiple linear regression and generalized estimating equations assessed associations between GNRI and EQ-5D utility scores.
resultsOf the 1092 patients, 947 were eligible for the research. The ROC of GNRI for predicting mortality was set. (AUC 0.726, 95% CI 0.687–0.766) Patients in Q2, Q3 and Q4 had significantly lower mortality risks (HRs 0.68, 95% CI 0.48–0.97; 0.47, 95% CI 0.31–0.72; and 0.23, 95% CI 0.13–0.42, respectively) comparing to Q1. Even after applying propensity score matching (PSM), individuals with higher GNRI still remained lower mortality risk. (HRs 0.56, 95% CI 0.34–0.91 and 0.55, 95% CI 0.36–0.85) Compared to Q1, patients in Q4 had a significantly increased possibility of achieving recovery at 1-year (OR 1.71, 95% CI 1.03–2.83, P = 0.037) and 3-year (OR 1.77, 95% CI 1.02–3.07, P = 0.042) follow-up. Admission GNRI was positively associated with EQ-5D utility scores at all follow-ups’ assessments (all P < 0.001), patients with higher GNRI exhibited better quality of life.
conclusionsThe GNRI upon admission is potentially a reliable and independent prognostic indicator of long-term mortality, functional status and quality of life in Chinese geriatric hip fracture patients.
trial registrationThis study was prospectively registered at ClinicalTrials.gov (Identifier: NCT03184896, Registration Date (First Posted): 2017-06-14) prior to the enrollment of participants.
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