ArticleBMC cardiovascular disorders2026
Lesion formation and impedance dependence of v-HPSD ablation (QDOT-MICRO™) versus conventional power-control (SmartTouch™ SF): a head-to-head comparison in an ex vivo porcine model.
Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study aims to compare the lesion characteristics of v-HPSD and conventional PC ablation modes and to quantitatively evaluate their dependence on impedance variation.
methodsThe study was performed using an ex vivo porcine heart model. Ablations in the v-HPSD group were carried out with a QDOT-MICRO™ catheter, whereas conventional power-control (PC) ablations employed a Thermocool-STSF® catheter, set at a fixed power of 40 W and terminated upon reaching an ablation index of 500. To study the effect of baseline impedance, it was dynamically adjusted to low, medium, and high preset levels by incorporating a sliding rheostat in series with the ablation circuit.
resultsAblation lesions in the PC group were characterized by significantly smaller superficial and maximum diameters but greater depth compared to the v-HPSD group (Superficial diameter: 5.19±0.71 mm vs. 5.83±0.73 mm, p<0.01; Maximum diameter: 7.04±0.95 mm vs. 7.79±0.96 mm, p<0.01; Depth: 4.67±0.22 mm vs. 3.50±0.40 mm, p<0.01). Although the mean lesion volume was larger in the PC group, this difference did not reach statistical significance (74.08±30.02 mm³ vs. 65.98±21.99 mm³, p=0.097). The ablation mode and impedance level demonstrated a significant interaction, which differentially affected the lesion parameters: highly significant for maximum depth and mean volume (P < 0.001), significant for superficial diameter (P < 0.05), and non-significant for maximum diameter (P = 0.587).
conclusionThe v-HPSD mode exhibits superior adaptability, achieving comparable overall lesion volume in high-impedance settings by generating wider and depth-stable lesions, which underscores its enhanced performance predictability.
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