ArticleInternational journal of behavioral medicine2026
Patient Views on a Pre-treatment Blood Test to Predict Outcomes Following PD-1 Inhibitor Therapy: A Qualitative Study.
Article in International journal of behavioral medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundAnti-PD-1 immunotherapy is routinely used to treat advanced melanoma cancer despite producing therapeutic benefits in less than half of patients. Given that this treatment can be associated with severe adverse effects, researchers are working to develop biomarker-based tests to predict the likely response to treatment. This study aimed to qualitatively explore patients' views on the value of such tests and how they would affect their treatment decision-making.
methodSemi-structured interviews were conducted with melanoma patients commencing PD-1 inhibitor therapy (n = 14), who were presented with a hypothetical scenario in which a blood-based biomarker prognostic test indicated the likely or unlikely success of anti-PD-1 immunotherapy.
resultsThematic analysis identified three major themes. (1) "More knowledge is more power": Perceived value and benefits of the test-all participants reported that such a test would be valuable, regardless of the outcome, as it would provide them with an expectation of treatment success and assist them with their treatment decision-making. (2) "It depends": Treatment decisions shaped by test outcome-participants described how the test outcome would affect their decision to undergo PD-1 inhibitor therapy. (3) "Faith in my doctor": Reliance on doctor's guidance for treatment decisions-participants stated that their treating doctor's opinion on their test outcome and subsequent advice would ultimately guide their treatment decision.
conclusionMelanoma patients see value in a test to predict anti-PD-1 immunotherapy response. An important consideration when communicating the outcome of this test is ensuring patients can discuss alternative treatment options and their recommendations for the best treatment option with their treating doctor.
Indexed as
Identifiers
41963753What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.