ArticleScientific reports2026
Immunoprophylactic potential against pneumonia caused by indigenous isolates of Klebsiella pneumoniae and Streptococcus pneumoniae in experimental mice.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pneumonia is a life threatening public health concern particularly due to multidrug resistant (MDR) bacterial pathogens. The rising threat of these resistant bacterial strains has exacerbated the challenge of treating bacterial pneumonia, emphasizing the urgent need of alternative therapeutic strategies such as vaccine development by targeting combined localized MDR bacterial pneumonia pathogens. In this study, clinical samples of bacterial pneumonia pathogens were collected from tertiary care hospitals of Lahore, Punjab, Pakistan. Strains were isolated and characterized on biochemical and molecular basis. The localized vaccines, including inactivated whole-cell vaccines, bivalent vaccine (KP + SP), combined vaccine (SP + LPS) and lipopolysaccharide (LPS)-based vaccines by targeting the most dominant bacterial pathogens K. pneumoniae and S. pneumoniae were prepared. The experimental trial was conducted on 7th, 14th, 48th, 60th and 90th days interval. Mice were immunized and immune responses were assessed using complement fixation test (CFT). Mice were challenged with a lethal dose (LD
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.