Evidence map›Paper›PMID 41962309›Full record

ArticleESMO open2026

Association of comprehensive inflammatory-metabolic status and perioperative outcomes in gastric cancer: insights from four randomized controlled trials.

L-K Zhang, Z-X Shang-Guan, H-L Zheng, H-H Zheng, C-Y Zheng, W-F Chen, J-W Xie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESMO open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

L-K ZhangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China; Fujian Province Minimally Invasive Medical Center, Fuzhou, China.
Z-X Shang-GuanDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China; Fujian Province Minimally Invasive Medical Center, Fuzhou, China.
H-L ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China; Fujian Province Minimally Invasive Medical Center, Fuzhou, China.
H-H ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China; Fujian Province Minimally Invasive Medical Center, Fuzhou, China.
C-Y ZhengDepartment of Gastrointestinal Surgery, The Affiliated Hospital of Putian University, Putian, China.
W-F ChenDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China; Fujian Province Minimally Invasive Medical Center, Fuzhou, China.
J-W XieDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China; Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China; Fujian Province Minimally Invasive Medical Center, Fuzhou, China. Electronic address: xjwhw2019@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory and metabolic status play a key role in the prognosis of gastric cancer (GC) patients. This study aimed to develop a novel comprehensive inflammatory-metabolic index (CIMI) to predict the risk of perioperative complications and prolonged hospital stay in GC patients. PATIENTS AND

methodsThis study included 567 stage II-III GC patients from four randomized, controlled trials RCTs as the development cohort, and 107 patients from an external cohort as the validation set. Preoperative hematological and body composition parameters were used to evaluate inflammatory-metabolic status. The predictive performance of CIMI was evaluated using receiver operating characteristic (ROC), precision-recall (PR), decision curve analysis (DCA) curves, and model fit indices [deviance, Akaike information criterion (AIC), Bayesian information criterion (BIC)]. Subgroup and survival analyses were conducted to further explore the clinical utility of CIMI.

resultsCIMI was calculated using the formula: log[white blood cell count (10

conclusionsAs a novel inflammatory-metabolic index, CIMI effectively predicts the risk of post-operative complications and prolonged hospital stay in GC patients, providing valuable insights for clinical decision-making and health care system strategies.

Indexed as

InflammationPostoperative ComplicationsStomach NeoplasmsAgedFemaleHumansLength of StayMaleMiddle AgedPrognosisRandomized Controlled Trials as Topicgastric cancerhospital stayinflammatory-metabolic indexpost-operative complicationspredictive model

Identifiers

PMID41962309
PMCPMC13091511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.