Evidence map›Paper›PMID 41961742›Full record

ArticleDermatology (Basel, Switzerland)2026

Evaluation of the Contribution of Repeat Total Body Photography for the Early Diagnosis of Melanoma.

Amjad Zoabi, Itay Shavit, Tomer Mimouni, Hana Feuerman, Ofer Reiter

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Article in Dermatology (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Amjad ZoabiSchool of Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Itay ShavitSchool of Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Tomer MimouniSchool of Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Hana FeuermanSchool of Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Ofer ReiterSchool of Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel, ofer.rtr@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Early detection of cutaneous melanoma is crucial, as prognosis is strongly determined by Breslow thickness. Total body photography (TBP) is increasingly used in high-risk populations, yet optimal surveillance strategies remain undefined. In our study, we aimed to evaluate how different follow-up approaches, including those incorporating TBP at varying frequencies, influence the early diagnosis of melanoma, as measured by Breslow thickness.

methodsThis retrospective cohort study included adult patients diagnosed with primary cutaneous melanoma at Rabin Medical Center between 2020 and 2025. Melanomas were classified into four groups according to the clinical setting at diagnosis: non-high-risk clinics, first visit to a high-risk clinic before TBP, high-risk follow-up with prior TBP only, and high-risk follow-up with both prior and repeat TBP on the day of diagnosis. Demographic, clinical, and histopathologic data were extracted. Differences in Breslow thickness were analyzed using analysis of covariance, and invasive versus in situ melanoma rates were assessed using multivariable logistic regression.

resultsA total of 282 melanomas from 249 patients were analyzed. Melanomas diagnosed in non-high-risk clinics were significantly thicker than those diagnosed in high-risk clinics (adjusted mean Breslow difference: 0.78 mm). Surveillance strategy was associated with invasiveness: invasive melanoma rates were highest in non-high-risk clinics (52%), followed by first visit to high-risk clinic (39%), patients with prior TBP only (34%), and lowest in patients diagnosed during repeat TBP (20%; overall model p = 0.03). Overall Breslow thickness did not differ significantly between melanomas diagnosed during visits with prior TBP alone and those diagnosed during repeat TBP.

conclusionHigh-risk melanoma clinics incorporating TBP are associated with earlier melanoma detection and lower rates of invasive disease. Repeated TBP was associated with lower rate of invasive melanoma compared with baseline TBP and manual comparison on the day of diagnosis. </p>.

Indexed as

Early Detection of CancerMelanomaPhotographySkin NeoplasmsWhole Body ImagingAdultAgedCutaneous Malignant MelanomaFemaleHumansMaleMiddle AgedRetrospective StudiesBreslow thicknessMelanomaSkin cancer screeningTotal body photography

Identifiers

PMID41961742
PMCPMC13275049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.