Evidence map›Paper›PMID 41961730›Full record

ArticleEnvironmental science & technology2026

An Integrated Approach Combining Regulatory Tests in

Florian Geffroy, Armelle Christophe, Benjamin Piccini, Nathalie Hinfray, Edith Chadili, Emmanuelle Maillot-Marechal, Xavier Cousin, Mélanie Blanc-Legendre, Thierry D Charlier, Pascal Pandard and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Florian GeffroyInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
Armelle ChristopheInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
Benjamin PicciniInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
Nathalie HinfrayInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
Edith ChadiliInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
Emmanuelle Maillot-MarechalInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
Xavier CousinMARBEC, Université de Montpellier, CNRS, Ifremer, IRD, Inrae, F-34250 Palavas-Les-Flots, France.ORCID 0000-0002-8520-3610
Mélanie Blanc-LegendreMARBEC, Université de Montpellier, CNRS, Ifremer, IRD, Inrae, F-34250 Palavas-Les-Flots, France.ORCID 0000-0002-3772-6978
Thierry D CharlierUniversité de Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail), F-35000 Rennes, France.
Pascal PandardInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
Selim Aït-AïssaInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.
François BrionInstitut National de l'Environnement Industriel et des Risques (INERIS), Parc Technologique ALATA BP2, F-60550 Verneuil-en-Halatte, France.ORCID 0000-0003-2341-4196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of efficient testing strategies for chemical hazard assessment is a current challenge in supporting regulatory requirements. Herein, we combined two zebrafish eleuthero-embryo assays, a refined Fish Embryo Acute Toxicity assay (FET, OECD TG 236) and the EASZY assay (OECD TG 250), both using transgenic tg(

Indexed as

Bisphenol A CompoundsToxicity TestsAnimalsAnimals, Genetically ModifiedBenzhydryl CompoundsEmbryo, NonmammalianEstrogensPhenolsZebrafishBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEstrogensPhenolsbisphenolsDanio rerioEASZYendocrine disruptionenvironmental hazard assessmentFETnew approach methodologies (NAMs)OECD test guidelines

Identifiers

PMID41961730
PMCPMC13130965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.