Evidence map›Paper›PMID 41961398›Full record

ArticleMagma (New York, N.Y.)2026

Effects of gadolinium-based contrast agents on the cardiac diffusion-weighted images of phantoms and patients.

Satonori Tsuneta, Satoru Aono, Jihun Kwon, Masami Yoneyama, Hiroki Uehara, Takuya Aoike, Sakae Takenaka, Hidenori Koyano, Noriyuki Fujima, Toshiyuki Nagai and 3 more

Abstract read
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Article in Magma (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Satonori TsunetaDepartment of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Nishi5, kita14, kita-ku, Sapporo, Hokkaido, 060-8648, Japan. satonori.tsuneta@pop.med.hokudai.ac.jp.ORCID http://orcid.org/0000-0003-0739-1975
Satoru AonoDepartment of Radiological Technology, Hokkaido University Hospital, Nishi5, kita14, kita-ku, Sapporo, Hokkaido, 060-8648, Japan.
Jihun KwonPhilips Japan, Ltd, Azabudai Hills Mori JP Tower 15F, 1-3-1 Azabudai, minato-ku, Tokyo, 106-0041, Japan.
Masami YoneyamaPhilips Japan, Ltd, Azabudai Hills Mori JP Tower 15F, 1-3-1 Azabudai, minato-ku, Tokyo, 106-0041, Japan.
Hiroki UeharaDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Nishi7, kita15, kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
Takuya AoikeDepartment of Radiological Technology, Hokkaido University Hospital, Nishi5, kita14, kita-ku, Sapporo, Hokkaido, 060-8648, Japan.
Sakae TakenakaDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Nishi7, kita15, kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
Hidenori KoyanoTechnical Support Center, Graduate School of Medicine, Hokkaido University, Nishi7, kita15, kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
Noriyuki FujimaDepartment of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Nishi5, kita14, kita-ku, Sapporo, Hokkaido, 060-8648, Japan.
Toshiyuki NagaiDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Nishi7, kita15, kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
Toshihisa AnzaiDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Nishi7, kita15, kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
Kazuyuki MinowaDepartment of Radiology, Graduate School of Dental Medicine, Hokkaido University, Nishi7, kita13, kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Kohsuke KudoDepartment of Diagnostic Imaging, Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University Graduate School of Medicine, Hokkaido University, Nishi7, kita15, kita-ku, Sapporo, Hokkaido, 060-8638, Japan.

Funding

JSPS KAKENHI JP23K14910
6 · The paper itself

Abstract

objectivesTo investigate the effects of gadolinium-based contrast agent (GBCA) on cardiac diffusion-weighted imaging (cDWI) and cDWI feasibility during the interval between GBCA administration and late gadolinium enhancement (LGE) imaging to streamline workflow. MATERIALS AND

methodsPhantoms containing varying GBCA concentration (0-1.0 mM/L) were scanned with stimulated echo acquisition mode-based cDWI (STEAM-cDWI) with various heart rates (HRs) (30-200 beats/min) and second-order motion-compensated spin-echo-based cDWI (M2SE-cDWI) with various echo times (TEs) (75-500 ms). For patient study, 9 patients underwent STEAM-cDWI and 13 underwent M2SE-cDWI before and after GBCA administration. Contrast ratio (CR) and contrast-to-noise ratio (CNR) between the left ventricular myocardium and cavity, and ADC values were assessed.

resultsIn phantoms, higher GBCA concentration, lower HR, and prolonged TE reduced SI. In STEAM-cDWI, CR and CNR significantly reduced after GBCA administration (CR of b = 400, 2.29 [1.80-5.46] vs. 1.15 [0.78-1.29], p = 0.0004; CNR of b = 400, 7.58 [4.82-11.1] vs. 0.57 [- 1.34 to 1.35], p = 0.0006; respectively); ADC values remained unchanged. In M2SE-cDWI, ADC values significantly decreased after GBCA administration (1.62 [1.15-1.97] vs. 1.26 [1.12- 1.51], × 10 DISCUSSION: cDWI is not recommended during the interval between GBCA administration and LGE imaging.

Indexed as

Cardiac imaging techniquesCardiomyopathiesDiffusion magnetic resonance imagingGadoliniumImage interpretation

Identifiers

PMID41961398

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.