Evidence map›Paper›PMID 41961185›Full record

ReviewIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2026

Prevalence of astrovirus-associated gastroenteritis among hospitalized pediatric patients in Asia: A systematic review and meta-analysis.

Bhavna Prajapati, Mudra Sikenis, Ashutosh Kumar Singh, Vishal Diwan, Uday Kumar Mandal, Surya Singh, Megha Katare Pandey, Karmveer Yadav, Rajnarayan R Tiwari, Pradyumna Kumar Mishra and 2 more

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Review in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Bhavna Prajapati *Division of Environmental Biotechnology, Genetics and Molecular Biology, ICMR - National Institute for Research in Environmental Health, Bhopal, 462 030, India.
Mudra Sikenis *Department of Life Science, Sharda School of Bio-science & Technology, Sharda University, Greater Noida, 201310, India.
Ashutosh Kumar SinghSchool of Biosciences, Engineering and Technology, VIT Bhopal University, Sehore, 466 114, India.
Vishal DiwanDivision of Environmental Monitoring and Exposure Assessment (Water & Soil), ICMR - National Institute for Research in Environmental Health, Bhopal, 462 030, India.
Uday Kumar MandalDivision of Environmental Health & Epidemiology, ICMR - National Institute for Research in Environmental Health, Bhopal, 462 030, India.
Surya SinghDivision of Environmental Monitoring and Exposure Assessment (Water & Soil), ICMR - National Institute for Research in Environmental Health, Bhopal, 462 030, India.
Megha Katare PandeyDepartment of Translational Medicine, All India Institute of Medical Sciences, Bhopal, 462 020, India.
Karmveer YadavDivision of Environmental Biotechnology, Genetics and Molecular Biology, ICMR - National Institute for Research in Environmental Health, Bhopal, 462 030, India.
Rajnarayan R TiwariFaculty of Medical Research, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India.
Pradyumna Kumar MishraDivision of Environmental Biotechnology, Genetics and Molecular Biology, ICMR - National Institute for Research in Environmental Health, Bhopal, 462 030, India.
Vikas YadavFaculty of Medical Research, Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India.ORCID http://orcid.org/0000-0002-0435-3386
Ram Kumar NemaDivision of Environmental Biotechnology, Genetics and Molecular Biology, ICMR - National Institute for Research in Environmental Health, Bhopal, 462 030, India. ramkumarnema@gmail.com.ORCID http://orcid.org/0009-0003-9151-4874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundViral gastroenteritis is a significant public health concern in developing countries, primarily affecting children under five years. Human astrovirus (HAstV) is one of the key viral agents causing gastroenteritis. Despite the global recognition of HAstV as a causative agent of acute gastroenteritis, its impact on Asian populations, particularly among hospitalized children, is lacking. This systematic review and meta-analysis aimed at determining the prevalence of HAstV-associated acute gastroenteritis among hospitalized pediatric patients in Asia.

methodThis systematic review and meta-analysis was conducted following PRISMA Guidelines and registered with PROSPERO (ID CRD42024519527). A comprehensive literature search was performed on PubMed, Web of Science and Scopus databases for studies published between January 2000 and December 2023. Keywords related to astrovirus, prevalence, pediatric populations and hospitalization in Asia were used. A pre-designed Excel sheet was used for data extraction and the Joanna Briggs Institute critical appraisal tool was used for quality assessment. Generalized Linear Mixed Models with logit transformation were used to calculate the effect sizes.

resultsThe analysis included 49 studies, encompassing data from various Asian countries. The pooled prevalence of HAstV in hospitalized pediatric patients due to acute gastroenteritis was 2.39%, highlighting the significant burden in Asia. Sub-group analysis revealed considerable difference in HAstV prevalence among Asian countries.

conclusionsThis systematic review and meta-analysis summarizes the prevalence of HAstV among hospitalized pediatric patients in Asia, highlighting the need for country-specific strategies to improve surveillance and diagnostics.

Indexed as

Acute gastroenteritisAsiaHospitalizedHuman astrovirus (HAstV)Pediatric patientsPrevalence

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.