Evidence map›Paper›PMID 41961137›Full record

ArticleFish physiology and biochemistry2026

Ocean acidification induces neuronal hyperexcitation and anxiety-like behaviour in marine medaka via ASIC activation.

Wenxiao Liu, Zhaofei Gong, Hao Niu, Jinghui Cui, Xiaojie Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenxiao LiuNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China.
Zhaofei GongNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China.
Hao NiuNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China.
Jinghui CuiNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China.
Xiaojie WangNational Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai, China. xj-wang@shou.edu.cn.ORCID http://orcid.org/0000-0001-7487-8092

Funding

National Key Research and Development Program of China 2018YFDO900902
6 · The paper itself

Abstract

Ocean acidification presents a significant threat to marine life, yet its neurobiological mechanisms remain poorly understood. This study examined how acid-sensing ion channels (ASICs) mediate neuronal excitability and anxiety-like behaviour in marine medaka (Oryzias melastigma) under elevated CO

Indexed as

Acid Sensing Ion ChannelsAnxietyNeuronsOryziasSeawaterAnimalsBehavior, AnimalCarbon DioxideHydrogen-Ion ConcentrationMembrane Potential, MitochondrialOcean AcidificationAcid Sensing Ion ChannelsCarbon DioxideAcid sensitive ion channelsAnxiety-like behaviourElectrophysiologyOcean acidificationUltrastructure

Identifiers

PMID41961137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.