ArticleVeterinary medicine and science2026
Investigating the Therapeutic Potential of Tamarix aphylla Leaf Extract Against Toxicity Caused by Graphene Nanosheets in Cirrhinus mrigala.
Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND AND
objectiveGraphene nanosheets (GNS) have found more applications in biomedical and industrial uses, but exposure to GNS can cause adverse health outcomes, such as oxidative stress, inflammatory responses, and tissue injury, depending on their dose and physicochemical characteristics. This study evaluates the potential of Tamarix aphylla leaf extract to mitigate GNS toxicity in Cirrhinus mrigala.
methodsConducted under controlled conditions, the research comprised two phases. Phase I determined the 96-h LC
resultsHigh-performance liquid chromatography (HPLC) identified key bioactive compounds in the extract, including ferulic, chlorogenic, gallic, p-coumaric, and caffeic acids, along with malic, citric, and oxalic acids. Malic acid was the predominant compound. Histopathological analysis revealed GNS-induced damage in the liver, kidney, and intestine, such as necrosis, sinusoidal dilation, and glomerulopathy. However, these effects were significantly reduced in extract-treated groups, highlighting the protective role of antioxidants and organic acids in the extract.
conclusionThe findings suggest that T. aphylla leaf extract effectively reduces GNS toxicity, offering a promising therapeutic strategy for mitigating the environmental impact of graphene-related pollutants.
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