Evidence map›Paper›PMID 41960995›Full record

ArticleRadiology. Imaging cancer2026

Automated Deformable Registration and Three-dimensional Margin Assessment for Predicting Local Recurrence after Lung Thermal Ablation.

Krishna Nand Keshavamurthy, Robert Salkin, Anirudha Shastri, Vlasios Sotirchos, Constantinos T Sofocleous, Ruben Geevarghese, Erica Alexander, Stephen B Solomon, Etay Ziv

Abstract read
In one paragraph

Article in Radiology. Imaging cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Krishna Nand KeshavamurthyDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0000-0003-2408-7414
Robert SalkinDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0009-0006-6342-446X
Anirudha ShastriDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.
Vlasios SotirchosDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0000-0001-7278-1369
Constantinos T SofocleousDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0000-0002-3142-1399
Ruben GeevargheseDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0000-0002-8461-0011
Erica AlexanderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0000-0001-7880-3565
Stephen B SolomonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0000-0001-5108-1021
Etay ZivDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Howard 118, New York, NY 10065.ORCID 0000-0002-3188-0085

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Purpose To develop a lung-specific deformable image registration algorithm optimized for lung thermal ablation and evaluate whether three-dimensional (3D) margin assessment predicts time to local recurrence. Materials and Methods This institutional review board-approved, single-institution retrospective study evaluated patients who underwent lung thermal ablation with available pre- and postprocedural CT scans suitable for deformable registration. Images were preprocessed with segmentation of tumor, ablation zone, and lung. A four-stage deformable image registration framework was applied:

Indexed as

Ablation TechniquesImaging, Three-DimensionalLung NeoplasmsNeoplasm Recurrence, LocalTomography, X-Ray ComputedAgedAlgorithmsFemaleHumansMaleMargins of ExcisionMiddle AgedRetrospective StudiesAblation TechniquesComputational StudiesComputer Applications-3DCTInterventional-OncologyLungPercutaneousThorax

Identifiers

PMID41960995
PMCPMC13231204

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.