Evidence map›Paper›PMID 41960792›Full record

ArticleJournal of natural products2026

Multilevel Residual Complexity Analysis Reveals Origin of Nanomolar Antiviral Bioactives of "Isoquercitrin".

Daniela Rebollar-Ramos, Annie V Roy, J Brent Friesen, Guy Harris, Shao-Nong Chen, Michael Chan, Shihua He, Guodong Liu, Wenjun Zhu, Logan Banadyga and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniela Rebollar-RamosPharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60612, United States.
Annie V RoyFunctional Endoproteolysis Laboratory, Montreal Clinical Research Institute, Montreal, Quebec H2W1R7, Canada.ORCID 0000-0001-5754-3514
J Brent FriesenPharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-0739-9224
Guy HarrisPharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60612, United States.
Shao-Nong ChenPharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-0748-0863
Michael ChanSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg ,ManitobaR3E3R2, Canada.
Shihua HeSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg ,ManitobaR3E3R2, Canada.
Guodong LiuSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg ,ManitobaR3E3R2, Canada.
Wenjun ZhuSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg ,ManitobaR3E3R2, Canada.
Logan BanadygaSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg ,ManitobaR3E3R2, Canada.
James B McAlpinePharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-1696-8828
Michel ChrétienFunctional Endoproteolysis Laboratory, Montreal Clinical Research Institute, Montreal, Quebec H2W1R7, Canada.
Majambu MbikayFunctional Endoproteolysis Laboratory, Montreal Clinical Research Institute, Montreal, Quebec H2W1R7, Canada.ORCID 0000-0003-4854-6507
Guido F PauliPharmacognosy Institute and Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-1022-4326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The remarkable reported

Indexed as

Antiviral AgentsQuercetinAnimalsEbolavirusHEK293 CellsHumansMolecular StructureSARS-CoV-2Spike Glycoprotein, CoronavirusZika VirusAntiviral AgentsisoquercitrinQuercetinSpike Glycoprotein, Coronavirus

Identifiers

PMID41960792
PMCPMC13122639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.