Evidence map›Paper›PMID 41960756›Full record

ArticleTurkish journal of pharmaceutical sciences2026

Assessment of the Potential Health Risks Associated with the Toxic and Essential Elements Content in Tea Samples Marketed in Türkiye.

Muhammed Hamitoğlu, Mert Şahin, Gülşah Esen, Sinem Helvacıoğlu, Ahmet Aydın

Abstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammed HamitoğluYeditepe University Faculty of Pharmacy, Department of Toxicology, İstanbul, TürkiyeORCID 0000-0002-4545-0756
Mert ŞahinYeditepe University Faculty of Pharmacy, Department of Toxicology, İstanbul, TürkiyeORCID 0009-0005-3275-0054
Gülşah EsenYeditepe University Faculty of Pharmacy, Department of Toxicology, İstanbul, TürkiyeORCID 0009-0002-8326-5911
Sinem HelvacıoğluVrije Universiteit Brussel Faculty of Medicine and Pharmacy, Department of Pharmaceutical and Pharmacological Sciences, Brussels, BelgiumORCID 0000-0002-3144-5024
Ahmet AydınYeditepe University Faculty of Pharmacy, Department of Toxicology, İstanbul, TürkiyeORCID 0000-0003-3499-6435

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Tea is a widely consumed beverage that may contain both essential and toxic metals, raising nutritional and health concerns. This study evaluated the transfer of selected essential and toxic metals from black tea leaves to their infusions and assessed the associated health risks and nutritional contributions. Materials and Methods: Black tea leaves and their infusions from eight commercially available brands sold in Türkiye were analyzed. Toxic elements [arsenic (As), aluminium, cadmium (Cd), lead (Pb)] were quantified using inductively coupled plasma mass spectrometry, while essential elements [copper, iron (Fe), magnesium (Mg), zinc] were quantified using flame atomic absorption spectrometry. Health risks were evaluated using the Estimated Daily Intake, the Target Hazard Quotient (THQ), the Hazard Index (HI), and the Incremental Lifetime Cancer Risk (ILCR). Results: In dry tea leaves, aluminum was the predominant toxic element (12.6–25.3 mg/g), followed by Pb (21.0–39.0 μg/g); As and Cd were present at lower levels. Mg (523.0–1421.0 μg/g) and Fe (263.1–445.5 μg/g) were the most abundant essential elements. Metal concentrations in tea infusions were significantly lower than those in dry leaves ( Conclusion: The transfer of metals from tea leaves to infusions is limited, likely due to chelation and complexation during brewing. Under typical consumption conditions, black tea infusions were within established safety limits, with risk indices below thresholds of concern. While As warrants continued monitoring, essential elements contribute only a small fraction of the recommended daily intakes. The small sample size is a limitation.

Indexed as

Cancer slope factorestimated Incremental Lifetime Cancer RiskHazard IndexHazard Quotientmetal contamination

Identifiers

PMID41960756
PMCPMC13360775

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.