SynthesisEuropean eating disorders review : the journal of the Eating Disorders Association2026
Associations Between Baseline Severity and Treatment Effects in Digital Interventions for Eating Disorders: A Meta-Regression.
Synthesis in European eating disorders review : the journal of the Eating Disorders Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Associations Between Baseline Severity and Treatment Effects in Digital Interventions for Eating Disorders: A Meta-Regression.European eating disorders review : the journal of the Eating Disorders Association · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWhile it is assumed that digital interventions are more suitable for milder eating disorder presentations, the evidence supporting this assumption remains unclear. We conducted meta-regressions testing whether baseline severity at the study level was associated with treatment effects from digital interventions for eating disorders.
methodDatabases were searched to identify RCTs of digital interventions compared to controls in individuals with diagnostic, subthreshold, or self-reported eating disorders. Baseline severity was operationalised as global levels of eating disorder psychopathology and objective binge eating. We conducted bivariable and multivariable meta-regressions to test whether baseline severity was associated with treatment versus control effect sizes and dropout.
resultsThirty-one trials were included. Bivariable meta-regressions showed that higher average objective binge eating was associated with greater treatment effect sizes and lower dropout rates. These associations remained significant in most sensitivity analyses, but not in the multivariable meta-regressions. Average global eating disorder psychopathology levels at baseline were not associated with treatment effects in bivariable meta-regressions, but was significantly and positively associated with effects in the multivariable model that adjusted for other characteristics.
conclusionHigher baseline severity may not limit the effectiveness or acceptability of digital interventions and in some contexts be associated with larger effects.
trial registrationhttps://osf.io/j9chm/overview.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.